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2010 Caliper Owners Group (COG) Meeting

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Join us for our Annual 2010 Owners Group (COG) and User Meeting! This year Caliper will be having 3 meetings at 3 venues.

Our scientific program is now underway and promises to deliver powerful insights into new and advanced research programs leveraging Caliper offerings.  You'll have more opportunity to network with colleagues while sharing information on best practices and participating in thought-leadership discussions.


Click on the venue of interest for detailed venue information and program agenda.


San Francisco, CA - Tuesday, May 18, 2010     THIS EVENT IS CLOSED
**REGISTRATION FOR THIS EVENT IS CLOSED**

Embassy Suites International Airport
250 Gateway Blvd.
South San Francisco, CA  94080
Tel:  (650) 589-3400

   
   Two Tracks

     (1) Microfluidic Technology
     (2) In Vivo Imaging

 

 Preliminary Agenda

 Tuesday, May 18, 2010  ♦  8:30 AM - 5:00 PM

  8:30 AM -  9:00 AM  Continental Breakfast & Registration

  MICROFLUIDIC TECHNOLOGY TRACK

 9:00 AM -  9:15 AM Welcome and Introductions
Mark Roskey, Sr. VP Applied Biology R&D and Isaac Meek, Associate Director of Marketing

 

Session One (Morning) - Proteomics/Genomics

 9:15 AM - 9:40 AM Microfluidic Protein Analysis at the Seattle Structural Genomics Center for Infectious Disease
Amy Raymond, Emerald Biostructures
 9:40 AM - 10:05 AM PhyNexus Separation and Purification with Caliper Robotics and LabChip Technologies Solutions for High Throughput Protein Analytics
Alexander Kuklin, Phynexus, Inc.
 10:05 AM - 10:30 AM Next Generation BioFuels: Analytical Tools, Automation Challenges
Masood Hadi, Sandia National Labs
 10:30 AM - 10:45 AM

BREAK

 10:45 AM - 11:10 AM High Throughput Analysis of Research and Therapeutic Proteins
Bahram Fathollahi, Caliper Life Sciences
 11:10 AM - 11:30 AM The Macrolab: Harnessing the Power of Automation to Solve Problems in Cloning and Protein Purification
Abbey Hartland, MacroLab Core Facility, University of CA - Berkeley
 11:30 AM - 11:55 AM An Automated System for a Non-Invasive Gene Expression Based Coronary Artery Disease Diagnostic Test
Jon Marlowe, Cardio DX
 11:55 AM - 12:30 PM Applications in Genomics:  New Tools for Next Generation Sequencing and Sample Processing
Isaac Meek, Caliper Life Sciences
12:30 PM  - 1:30 PM

LUNCH

 

Session Two (Afternoon) - Small Molecule Drug Discovery

 1:30 PM - 1:55 PM Dusp-5: A Putative Target for Vascular Disease
Ramani Ramchandran, Medical College of Wisconsin
 1:55 PM - 2:20 PM Cathepsin S Inhibitor Drug Development in a Virtual Company Model Using Caliper Discovery Alliances and Services
Leslie Holsinger, Virobay
 2:20 PM - 2:45 PM Internal Kinase Selectivity Screening Made EZ
Laurie Lebrun, Celgene Corporation
 2:45 PM -3:00 PM

BREAK

 3:00 PM - 3:25 PM Development, Validation and Implementation of an Assay for Identifying Inhibitors of Soluble Adenyl Cyclase Using the Caliper LC3000
Derek Hook, University of Minnesota
 3:25 PM - 3:50 PM Lead Generation for a Novel Prostate Cancer Target using a Comprehensive Fragment Screening Strategy
Karen Maegley, Pfizer
 3:50 PM - 4:15 PM Caliper Profiling Service in GNF Drug Discovery
Yong Jia, Genomics Institute of Novartis Research Foundation
 4:15 PM - 4:45 PM Lighting Up Metabolism:  Novel In Vivo Imaging Approaches from Ligpid Uptake
Andreas Stahl, University of California, Berkeley
 5:00 PM

COCKTAIL RECEPTION

   
   

 IN VIVO IMAGING TRACK

 9:00 AM - 9:30 AM Welcome and Introductions
Anna Christensen, Imaging Product Manager and Stephen Oldfield, Imaging Marketing Manager
 

Session One (Morning) - User Presentations

 9:30 AM - 10:00 AM Optical Imaging of Cancer Models:  The UCSF Preclinical Therapeutic Core
Byron Hann, UCSF
 10:00 AM - 10:30 AM Lighting Up Metabolism:  Novel In Vivo Imaging Approaches from Lipid Uptake
Andreas Stahl, University of California, Berkeley

 10:30 AM - 11:00 AM

BREAK

 11:00 AM - 11:30 AM Using Bioluminescent Imaging to Understand the Pharmacokinetic / Pharmacodynamic Relations Following Treatment with siRNA
Nelly A Kuklin, Ph.D., Merck Research Laboratories/Sirna Therapeutics
 11:30 AM - 12:00 PM TBD
 12:00 PM - 12:30 PM X-ray Dosage Modeling for MicroCT of Small Animals
Magdalena Bazalova, Stanford University School of Medicine

 12:30 PM - 1:30 PM

LUNCH

 

Session Two (Afternoon) - User Presentations

  1:30 PM - 2:00 PM New Developments in In Vivo Chemistries for Small Animal Imaging
Rajendra Singh, Director of Assay Development Caliper Life Sciences
  2:00 PM - 2:30 PM IVIS Imaging
Jonathan Hardy, Stanford University

  2:30 PM - 3:00 PM

BREAK

  3:00 PM - 3:30 PM

Advances in 3D Optical Imaging Technology
Brad Rice, Sr VP of Systems R&D Caliper Life Sciences

  3:30 PM - 5:00 PM

Hands on Living Image Software Workshop
Anna Christensen, Imaging Product Manager

  5:00 PM

COCKTAIL RECEPTION

   
La Jolla, CA - Thursday, May 20, 2010   THIS EVENT IS CLOSED
**REGISTRATION FOR THIS EVENT IS CLOSED**




Hilton La Jolla Torrey Pines
10950 N. Torrey Pines Road              
La Jolla, CA 92037
Tel:  (858) 558-1500
  

 

 Preliminary Agenda

 Thursday, May 20, 2010  ♦  8:30 AM - 5:00 PM

  8:30 AM -  9:00 AM Continental Breakfast & Registration
  9:00 AM -  9:30 AM Welcome Presentation

  9:30 AM - 12:30 PM

Morning Session User Presentations

  Biologics/Vaccines/Protein Science & Genomics/Molecular Diagnostics
Moderators:  Bahram Fathollahi (Biologics) & Isaac Meek (Genomics)
  Analytical Capabilities of LabChip Technology
Migani Damiano, Biogen Idec Pharmaceuticals
  Fully Automated Sample Processing and HTP Microchip CGE Analysis for Rapid Identification of Microbial Production Strains Using PfÄ“nex Expression Technology™
Jeff Allen, Pfenex Inc.
  PhyNexus Separation and Purification with Caliper Robotics and LabChip Technologies Solutions for High Throughput Protein Analytics
Christopher Suh, PhyNexus Inc.
  High Throughput Analysis of Research and Therapeutic Proteins
Bahram Fathollahi, Caliper Life Sciences
  Genome, Epigenome, and Transcriptome Study by Deep-Sequencing using Next Generation Sequencing Technology
Ryan Kim, National Center for Genomic Resources
  High Throughput PCR process for Finishing Genomes
Beverly Parsons, Los Alamos National Labs - Joint Genome Institute
  High-Throughput Nucleic Acid Purification solutions on Zephyr Genomics Workstation
Mimi Ly, Machery Nagel (Bjoern Henze)
  New Applications if Genomics
Isaac Meek, Caliper Life Sciences
10:45 AM - 11:00 AM

Break

11:00 AM - 12:30 PM

Resume Session One Presentations

12:30 PM  -  1:30 PM

Lunch/Presentations/Keynote

 1:30 AM  - 4:30 PM

Afternoon Session User Presentations

  Small Molecules Drug Discovery
Moderator:  Seth Cohen
  Inhibition of a Kinase Involved in Insulin Signaling
Siobhan Malaney, Formerly from Tanabe
  Internal Kinase Selectivity Screening Made EZ
Laurie Lebrun, Celgene Corporation
  Generation for a Novel Prostate Cancer Target using a Comprehensive Fragment Screening Strategy
Karen Maegley, Pfizer Inc.
  Caliper Profiling Service in GNF Drug Discovery
Yong Jia, Genomics Institute of Novartis Research Foundation
  Development, Validation and Implementation of a assay for identifying inhibitors of souble adenyl cyclase using the Caliper LC3000
Derek Hook, University of Minnesota
  Expand the Capabilities of Your Caliper Robot: Incorporate V&P Scientific's Pin Tools and Robotic Accessories
Mary Harper, VP Scientific
  New Applications in Drug Discovery
Raj Singh, Caliper Life Sciences
   
  Optical Imaging Applications & Technology
Moderator:  Stephen Oldfield
  Establishment and Characterization of a New Imaging Model for the Study of Human Hematopoietic Disease Progression in Mice
Max Hallan, Pfizer
  New Approaches in Molecular Imaging for Skeletal Tissue Regeneration
Wafa Tawackoli, Cedar Sinai Medical Center
  In Vivo Imaging of Metastatic Breast Cancer Progression and Response to Treatment in Animal Models
Mihaela Lorger, The Scripps Research Institute
  2:45 PM - 3:00 PM

Break

  3:00 PM - 5:00 PM

Resume Session Two Presentations

  5:00 PM - 6:00 PM

Cocktails

   
Hopkinton, MA - Wednesday & Thursday, June 9-10, 2010     THIS EVENT IS CLOSED
Caliper Life Sciences
Corporate Headquarters            
68 Elm Street
Hopkinton, MA  01748
Tel: (508) 435-9500

 

 Preliminary Agenda

 Wednesday, June 9, 2010  ♦  8:30 AM - 5:00 PM

  8:30 AM -  9:00 AM Continental Breakfast & Registration  
  9:00 AM -  9:05 AM Welcome  
  9:05 AM - 9:30 AM Keynote Speaker - George Church, Harvard Medical  

  9:30 AM - 12:30 PM

Session One (Morning) User Presentations  

Track 1Biologics/Vaccines/Protein Science
Moderator:  Bahram Fathollahi
 
  High Throughput Analysis of Research and Theraputic Proteins
Bahram Fathollahi, Caliper Life Sciences
 
  Implementation of LabChip Methods in Quality Control to Replace SDS-PAGE for Release and Stability Testing
Stacey Traviglia, Bioden Idec
 
  Replacing SDS-PAGE:  Comparison of Caliper GXII to Other CE Platforms
Michael Smith, GSK
 
  PhyNexus Separation and Purification with Caliper Robotics and LabChip Technologies Solutions for High Throughput Protein Analytics
Lee Hoang, PhyNexus Inc.
 
  Protein QC, Method Development and Determination of Aggregation Status Using Caliper GXII
Kallol Ray, Merck
 
     
  Track 2 - Optical Imaging Applications & Technology
Moderator:  Stephen Oldfield/Dave Panzarella
 
  In vivo imaging as a tool for the development of M402, a novel HSPG mimetic oncology candidate
Ed Cochran, Momenta Pharmaceuticals
 
  Spectral unmixing with a “smart” fluorescence probe: An application for imaging amyloid beta species
Chongzhao (Ron) Ran, Harvard University
 
  A Bioluminescent Transgenic Mouse Model to Monitor CREB Transcriptional Activation
Ken Miller, Pfizer
 
10:45 AM - 11:00 AM

Break

 
11:00 AM - 12:30 PM

Resume Session One Presentations

 
12:30 PM  -  1:30 PM

Lunch/Presentations

 

 1:30 AM  - 4:30 PM

Session Two (Afternoon) User Presentations  
  Track 1 - Small Molecule Drug Discovery
Moderator:  Seth Cohen
 
  The use of Caliper Life Science Microfluidic Technology to Define a New Hit Discovery Paradigm
Adam Shutes, EMD Merck
 
  Discovery & Development of Next Generation Kinase Inhibitors at ArQule
Dennis France, Arqule Corporation
 
  “Channeling” the Discovery of Chemical Probes for Methyl-Lysine
Tim Wigle, Univ. of North Carolina
 
  Metabolic Stability: 384 or 96 Well, What's Your Throughput?
Mark Snyder, Pfizer
 
     
  Track 2 - Genomics/Molecular Diagnostics
Moderator:  Isaac Meek
 
  Integration of the Caliper GX as a Quality Checkpoint for High Throughput Next Generation Sequencing Sample Preparation
Andrew Barry, Broad Institute
 
  High-Throughput Nucleic Acid Purification solutions on Zephyr Genomics Workstation
Laura Ficociello, Machery Nagel (Bjorn Henze)
 
  DNA Polymerase Development via Microfluidics and Database-Integrated Analysis
Nicole Nichols, New England Biolabs
 
  K-Ras Mutation Detection
Ben Legendre, Transgenomics
 
  Implementation of the LabChip GX into the Clinical Laboratory Setting
Dave Olson, Access Genetics
 
  2:45 PM - 3:00 PM

Break

 
  3:00 PM - 4:40 PM

Resume Session Two Presentations

 
  4:30 PM - 5:00 PM

Wrap Up

 
  5:00 PM - 6:00 PM

Cocktails & Beer (Ipswich Brewery Truck arrives), DJ arrives

 
  6:00 PM - 9:00 PM

Dinner (Traditional NE Clambake), Beer, Music, Dancing, RC Car Races and more!

 
     

 Thursday, June 10  ♦  8:30 AM - 5:00 PM

 
  8:30 AM  -  9:00 AM Continental Breakfast & Registration  
  9:00 AM  -  9:30 AM Welcome Presentation  

 9:30 AM - 12:30 PM

Session One (Morning) - User Presentations
 

Track 1 - Biologics/Vaccines/Protein Science
Moderator:  Bahram Fathollahi
 
  High Throughput Glycan Analysis in Support of Cell Line Screening
Pete Bryngelson, Biogen Idec
 
  Novel Analytical Technology to Support Biologics Process Development:  Caliper Life Sciences GXII Application Evaluation
Mei Lin, Bristol Myers Squibb
 
  Presentation Title - TBD
Narasaiah Dontha, Bristol Myers Squibb
 
  SWAP- A High Throughput Microfluidic Alternative for Western Blotting
Laurel Provencher, Caliper Life Sciences
 
     
  Track 2 - Optical Imaging Applications & Technology
Moderator:  Stephen Oldfield/Dave Panzarella
 
  Optical imaging of Cerenkov light generation from positron-emitting radiotracers
Matt Silva, Millennium Pharmaceuticals
 
  Applications for Optical imaging using positron-emitting radiotracers
Rob Robertson, Millennium Pharmaceuticals
 
  X-ray Dosage Modeling for MicroCT of Small Animals
Magdalena Bazalova, Stanford University School of Medicine
 
  IVIS and humanized mouse models: Applications for stem cells, viruses, and malaria
Jennifer Moffat, SUNY Upstate Medical University, Syracuse NY
 
 10:45 AM - 11:00 AM Break  
 11:00 AM - 12:30 PM Resume Session One Presentations  
 12:30 PM  -  1:30 PM Lunch/Presentations/Keynote  

 1:30 AM  -  4:30 PM

Session Two (Afternoon) User Presentations  

Track 1 - Small Molecule Drug Discovery
Moderator:  Seth Cohen
 
  Mechanism of Action- Industry and Academic Perspectives
Round Table Discussion
 
  Characterization of Slow-Binding HDAC Inhibitors by Caliper
Yan-Ling Zhang. the Broad Institute
 
  Application of Label-Free Assay Technology for Functional GPCR Drug Discovery: Enabling Screening and Complete Drug/Receptor Characterization Studies
Scott Perschke, Caliper Discovery Alliances & Services (CDAS)
 
  Beyond GPCRs: The BIND® Reader - A Universal Label-Free System to Interrogate Whole Cell, Functional Responses to a Wide Range of Biochemicals
Michael Getman, SRU BioSystems
 
  Supporting Kinase discovery programs with the Caliper EZReader
Bill Janzen, Univ. North Carolina
 
     
  Track 2 - Genomics/Molecular Diagnostics
Moderator:  Isaac Meek
 
  Presentation Title - TBD
Paul Ventura, Covaris Corporation
 
  Annotation and Phenotypic Analysis of Cancer-Associated Alternative Splicing
Roscoe Klinck, Univ. of Sherbrooke
 
  New Applications in Genomics
Isaac Meek, Caliper Life Sciences
 
  Alternative Sample Prep Solutions for Next Generation Sequencing
Nick Caruccio, Epicentre Biotechnologies
 
  2:45 PM - 3:00 PM Break  
  3:00 PM - 4:30 PM Resume Session Two Presentations  
  4:30 PM Wrap up  



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