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Cytochrome P450 , Pooled Human Liver Microsome (CYP3A4)

Cat#: 400-0934
Species: Human
RegionPooled Human Liver Microsomes ** 12 well minimum **
SubstrateTestosterone
Km (enzyme affinity)83uM
Vmax422 pmol /mg HLM pooled /min
ReactionTestosterone + NADPH --> 6-hydroxytestosterone + NADP+
MethodLC-MS/MS
Reference CompoundKetoconazole
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