Transporters
Transporters are integral membrane proteins involved in the movement of molecules by facilitated diffusion or active transport across a biological membrane. One class of these transporters is located in the synaptic membrane of neurons and serve to remove neurotransmitters from the synaptic cleft. Another class, also located in neurons, are called vesicular transporters and serve to move neurotransmitters into synaptic vesicles. Many of these transporters in are involved in psychiatric disorders. An additional group are the ATP-binding cassette transporters (ABC-transporters). They also are transmembrane proteins and function in the transport of a wide variety of substrates across extra- and intracellular membranes, including metabolic products, lipids and sterols, and drugs. ABC transporters are involved in drug resistance, cystic fibrosis, bacterial multi-drug resistance and a range of other inherited human diseases.| Cat# | Assay Type | Assay Class | Assay Name | $/Well (USD) |
|---|---|---|---|---|
| 300-0214 | Cellular | Adenosine | Transport AOT-T es (h) | $60.00 |
| 300-0215 | Cellular | Adenosine | Transport AOT-T es/cs (h) | $60.00 |
| 100-0047 | Binding | Adenosine | Transporter AOT | $39.00 |
| 100-0001 | Binding | Adenosine | Transporter AOT (h) | $62.00 |
| 300-0216 | Cellular | Anandamide | Transport AMT-T (h) | $60.00 |
| 300-0217 | Cellular | Choline | Transport CHOL-T | $38.00 |
| 300-0331 | Cellular | Dopamine | Transport, DAT-T | $60.00 |
| 100-0015 | Binding | Dopamine | Transporter, DAT | $44.00 |
| 100-0123 | Binding | Dopamine | Transporter, DAT (h) | $62.00 |
| 300-0218 | Cellular | GABA | Transport GABA-T | $38.00 |
| 300-0219 | Cellular | Glutamate | Transport GLUT-T | $38.00 |
| 300-0332 | Cellular | Norepinephrine | Transport NET-T | $38.00 |
| 300-0404 | Cellular | Norepinephrine | Transport NET-T (h) | $60.00 |
| 100-0048 | Binding | Norepinephrine | Transporter NET | $44.00 |
| 100-0146 | Binding | Norepinephrine | Transporter NET (h) | $62.00 |
| 100-0806 | Binding | P-Glyocoprotein (PGP) | Transporter P-Glycoprotein (PGP) (h) | $62.00 |
| 300-0220 | Cellular | Serotonin | Transport SERT-T (h) | $60.00 |
| 100-0056 | Binding | Serotonin | Transporter SERT | $44.00 |
| 100-0099 | Binding | Serotonin | Transporter SERT (h) | $62.00 |
| 300-0554 | Cellular | Vesicular Monoamine | Transport VMAT1 | $60.00 |
| 300-0555 | Cellular | Vesicular Monoamine | Transport VMAT2 | $60.00 |
| 100-0751 | Binding | Vesicular Monoamine | Transporter VMAT2 | $62.00 |