CYP Explorer

Metabolism related drug drug interactions play an important role in the high attrition rate observed in drug development. CDAS panels of CYP450 inhibition assays have been designed to provide an early, fast and inexpensive assessment of a compound potential to inhibit one or more specific CYP450 enzyme that could interfere with the normal metabolism of another drug. 

CYP Basic (6 assays) and CYP Regulatory (17 assays) panels investigate the CYP450 enzymes most commonly involved in drug drug interactions metabolism while CYP Explorer provides a thorough drug CYP450 inhibition profile and a useful resource to investigate molecular mechanisms of toxicity.

CYP Explorer is a panel of 31 Cytochrome, P450 assays covering a broad array of assays using both rat and human source material.

For more information on our CYP Explorer, other CYP programs or other assay services and panels, contact us at CDAS@caliperls.com.

Assay Code	Price/Compound	Format
A	$3720.00	1 concentration, duplicate
B	$5466.00	1 concentration, triplicate
C	$7136.00	2 concentrations, duplicate
D	$10477.00	3 concentrations, duplicate

Cat#	Assay Type	Assay Class	Assay Name
400-0905	Enzyme	CYP19, Aromatase (h)	CYP19, Aromatase (h)
400-0861	Enzyme	CYP1A1 (h)	CYP1A1 (h)
400-0862	Enzyme	CYP1A1 (rat)	CYP1A1 (rat)
400-0093	Enzyme	CYP1A2 (h)	CYP1A2 (h)
400-0864	Enzyme	CYP1A2 (rat)	CYP1A2 (rat)
400-0863	Enzyme	CYP1B1 (h)	CYP1B1 (h)
400-0891	Enzyme	CYP2A1 (rat)	CYP2A1 (rat)
400-0878	Enzyme	CYP2A2 (rat)	CYP2A2 (rat)
400-0094	Enzyme	CYP2A6 (h)	CYP2A6 (h)
400-0892	Enzyme	CYP2B1 (rat)	CYP2B1 (rat)
400-0860	Enzyme	CYP2B6 (h)	CYP2B6 (h)
400-0882	Enzyme	CYP2C11 (rat)	CYP2C11 (rat)
400-0885	Enzyme	CYP2C12 (rat)	CYP2C12 (rat)
400-0883	Enzyme	CYP2C13 (rat)	CYP2C13 (rat)
400-0868	Enzyme	CYP2C18 (h)	CYP2C18 (h)
400-0095	Enzyme	CYP2C19 (h)	CYP2C19 (h)
400-0884	Enzyme	CYP2C6 (rat)	CYP2C6 (rat)
400-0886	Enzyme	CYP2C8 (h)	CYP2C8 (h)
400-0096	Enzyme	CYP2C9*1 (h)	CYP2C9*1 (h)
400-0867	Enzyme	CYP2D1 (rat)	CYP2D1 (rat)
400-0866	Enzyme	CYP2D2 (rat)	CYP2D2 (rat)
400-0097	Enzyme	CYP2D6 (h)	CYP2D6 (h)
400-0876	Enzyme	CYP2E1 (h)	CYP2E1 (h)
400-0880	Enzyme	CYP2E1 (rat)	CYP2E1 (rat)
400-0879	Enzyme	CYP2J2 (h)	CYP2J2 (h)
400-0865	Enzyme	CYP3A1 (rat)	CYP3A1 (rat)
400-0881	Enzyme	CYP3A2 (rat)	CYP3A2 (rat)
400-0098	Enzyme	CYP3A4 (h)	CYP3A4 (h)
400-0869	Enzyme	CYP3A5 (h)	CYP3A5 (h)
400-0875	Enzyme	CYP4F12 (h)	CYP4F12 (h)
400-1050	Enzyme	CYP51 (h)	CYP51 (h)