iNOS-luc
Overview
iNOS-luc BP (P/N 119290) Breeding Pair or iNOS-luc (P/N 119312) Individual Animal
Light producing animal model (LPTA®) FVB/N-Tg(iNos-luc)-Xen, commonly called iNos-luc, carries a transgene using a 1.3 kb murine iNos promoter and modified firefly luciferase cDNA (Promega pGL-3). Basal expression of the reporter is undetectable in naïve mice. The reporter is inducible by IFN-γ and LPS in liver and by zymosan in knee joint. This LPTA® animal model is available from Taconic.| Model: | Inflammatory Model |
| Mouse Strain: | FVB/N-Tg(iNos-luc)Xen |
| Common Name: | iNos-luc |
| Genotype: | Hemizygote |
| Background Strain: | FVB/N |
| Coat Color: | Albino |
Applications
The iNos-luc LPTA® animal model is useful in studying sepsis, arthritis, and anti-inflammatory compounds.