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Vegfr2-luc

Overview


Vegfr2-luc
BP (P/N 119298) Breeding Pair or Vegfr2-luc (P/N 119320) Individual Animal

Light producing animal model (LPTA®) FVB/N-Tg(Vegfr2-luc)-Xen, commonly called Vegfr2-luc, carries a transgene containing a 4.5 kb murine VEGFR2 promoter and a modified firefly luciferase cDNA (Promega pGL-3). Basal expression or the reporter is observed in lung, testes, and uterus. The reporter is inducible during cutaneous wound healing and delayed type hypersensitivity reaction. This LPTA® animal model is available from Charles River Laboratories.


Model: Oncology/Angiogenesis Model
Mouse Strain: FVB/N-Tg(Vegfr2-luc)-Xen
Common Name: Vegfr2-luc
Genotype: Homozygous
Background Strain: FVB/N
Coat Color: Albino



Applications

The Vegfr2-luc LPTA® animal model is useful in studying a variety of angiogenic processes, including embryonic development, post-natal development, wound healing, and delayed type hypersensitivity.