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MDA-MB-231-luc2 Bioware® Ultra

Overview

MDA-MB-231-luc2 is a luciferase expressing cell line which was stably transfected with firefly luciferase gene (luc2). The cell line was established by transducing lentivirus containing luciferase 2 gene under the control of human ubiquitin C promoter. 

Designation
:  MDA-MB-231-luc2

Tissue:  Human: adenocarcinoma; mammary gland

Source of Parental Line
:  ATCC (HTB-26™)

Gene Transfer Vehicle:  pGL4 luc2  Lentivirus

Bioluminescence In Vitro:  Approximately 1300 photons/sec/cell.  Exact number will vary depending on imaging and culturing conditions.

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Applications

• Subcutaneous tumor models
• Experimental metastasis model (intravenous and intracardiac)
• Orthotopic mammary fat pad model with metastasis