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PC-3M-luc2 Bioware® Ultra

Overview

PC-3M-luc2 is a luciferase expressing cell line which was stably transfected with firefly luciferase gene (luc2). The cell line was established by transducing lentivirus containing luciferase 2 gene under the control of human ubiquitin C promoter. 

Designation:  PC-3M-luc2

Tissue:  Human; prostate; adenocarcinoma

Source of Parental Line:  MD Anderson Cancer Center, the University of Texas/ Novartis Institute for Biomedical Research

Gene Transfer Vehicle:  pGL4 luc2 Lentivirus

Bioluminescence In Vitro:  Approximately 1500 photons/sec/cell.  Exact number will vary depending on imaging and culturing conditions.

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Applications

• Subcutaneous tumor models
• Subcutaneous tumor models with metastasis (SCID-bg mice)
• Experimental metastasis models (intravenous and intracardiac)
• Orthotopic prostate tumor model