XenoLight RediJect Bone Probe 680
XenoLight RediJect Bone Probe 680 conjugate is a novel fluorescence reagent for targeting hydroxyapatite. Hydroxyapatite, a biomarker for osteoblast activity, is an essential component of normal bone. RediJect Bone Probe 680 conjugate, when used in conjunction with the IVIS imaging system, allows for in vivo detection, measurement and monitoring of skeletal changes in a variety of disease models including osteoarthritis.• Dispensed to image 5 animals (explorer kit) or 20 animals (standard kit)
• Detection of ectopic bone formation in vivo
• Identification of skeletons in non-invasive fluorescence imaging
• In vivo imaging quality, validated on IVIS imaging systems
RediJect Bone Probe 680 (Explorer kit)
RediJect Bone Probe 680 (Standard kit)
Fluorescent Imaging of RediJect Bone Probe 680 Targeting in Nu/Nu Mice
Free dye 680 (top row) and RediJect Bone probe 680 (bottom row) was injected into male nu/nu mice (2 nmol/mouse) through tail vein.
Fluorescent images were taken at various time points using an IVIS Lumina XR. Dorsal views are shown. Pre: pre-image before injection.
Features
Color and Form: Clear blue colored solution in PBS
Concentration: 2nmoles/150 ul
Volume per vial:
Explorer kit: 1 sterile amber vial containing 850 ul of 2nmoles/150 ul probe
Standard kit: 4 sterile amber vials containing 850 ul of 2nmoles/150 ul probe
Storage and Handling: Store the Rediject Bone Probe 680 conjugate at 4°C and protect from light. For in vivo imaging studies we recommend an intravenous injection of 150 ul/mouse. Allow the reagent to warm up to room temperature before injection in an animal
Dye Characteristics:
Peak Excitation: 681 nm, Peak Emission: 698 nm
Ideal IVIS Spectrum Filter Sets: 640 ex/700 em or 675 ex.720 em
Concentration: 2nmoles/150 ul
Volume per vial:
Explorer kit: 1 sterile amber vial containing 850 ul of 2nmoles/150 ul probe
Standard kit: 4 sterile amber vials containing 850 ul of 2nmoles/150 ul probe
Storage and Handling: Store the Rediject Bone Probe 680 conjugate at 4°C and protect from light. For in vivo imaging studies we recommend an intravenous injection of 150 ul/mouse. Allow the reagent to warm up to room temperature before injection in an animal
Dye Characteristics:
Peak Excitation: 681 nm, Peak Emission: 698 nm
Ideal IVIS Spectrum Filter Sets: 640 ex/700 em or 675 ex.720 em
