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Lab Automation and Liquid Handling Application Notes


 Drug Discovery

Compound Distribution form Matrix Screenmates Tubes using the Caliper Sciclone ALH 3000 (pdf)
Integration of an automated Workstation for Cell-Based Assays on Permeable Support Systems (pdf)
Improvements in High Content Cell-Based Assays using the Caliper Sciclone ALH 3000 and various Corning Microplates (pdf)
Miniaturization and Automation of a Luciferase Reporter Gene Assay (pdf)
 

 Genomics

High Throughput Plasmid DNA Preparation Using PVDF Filter Plates on an Automated Workstation (pdf)
High Throughput PCR Cleanup Using 384 Well Glass Fiber Filter Plates and Postive Pressure on an Automated Workstation (pdf)
Preparing Agilent 2100 LabChips for RNA analysis using the Caliper Sciclone ALH 3000 (pdf)
Sciclone ALH Carryover Testing Using the Ultrasonic Wash Station and a 384-Cannula Array (pdf)
Automation of the Eppendorf Perfectprep BAC 96 DNA Kit on the Caliper Life Sciences Sciclone ALH 3000 (pdf)
High Throughput Plasmid DNA Preparation Using a Megnetic Bead Kit on an Automated Workstation (pdf)
Scalable automation of the TempliPhi(tm) DNA Sequencing Template Amplification and DYEnamic(tm) ET Terminator Sequencing Kits on the Sciclone ALH 3000 (pdf)
Efficient, Automated RNA Isolation Using Ambion MagMAX-96 Total RNA Isolation Kit on the Sciclone ALH 3000 (pdf)
Automation of the Ambion MagMAX-96 Viral RNA Isolation Kit on the Sciclone ALH 3000 (pdf)
Automated Antisense RNA Synthesis Using the Ambion MessageAmp II-96 aRNA Amplification Kit (pdf)
 

 Proteomics

Protein Crystallization:  Sitting Drop Plate Screen Set-up using Corning's 96 Well Crystallography Plate and Caliper's Sciclone ALH 3000 (pdf)
 

 Performance Validation

Evaluation of Second Generation Disposable Tip Accuracy and Precision for the Sciclone ALH 3000 using the Artel MVS Calibration Kit (pdf)
Dry Dispensing with the Caliper Sciclone ALH 3000 using Disposable Tips (pdf)
Liquid Level Detection with the Caliper Sciclone ALH 3000 (pdf)
Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option (pdf)
Prolonged Mechanical Stress Precision Testing on a Sciclone ALH Low Volume Head (pdf)
Dispensing 0.5 uL to "Dry" 384 Plates with the Sciclone ALH (pdf)
Sciclone ALH Bulk Dispense Precision Testing (pdf)
384 Well Pipetting Precision and Accuracy Testing Using the Sciclone Advanced Liquid Handler (pdf)
96 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array (pdf)
Sciclone ALH 3000 Liquid Handler:  Functional Characterization of the High Volume Head: Plate-to-Plate Precision Testing (pdf)
 

 Method Writing Tips

ALH 3000 Software v3.5: Using Excel Instructions and a Plate Normalization Example (pdf)
Timing incubations using VBA in Caliper Sciclone Software v3.5 (pdf)
 
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