In Vivo Optical Imaging Publications

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2009

A Cre/LoxP conditional luciferase reporter transgenic mouse for bioluminescence monitoring of tumorigenesis

A matter of timing: unsynchronized antigen expression and antigen presentation diminish secondary T cell responses

A novel hTERT promoter-driven E1A therapeutic for ovarian cancer

A novel human Her-2/neu chimeric molecule expressed by Listeria monocytogenes can elicit potent HLA-A2 restricted CD8-positive T cell responses and impact the growth and spread of Her-2/neu-positive breast tumors

A pseudouridine synthase homologue is critical to cellular differentiation in Toxoplasma gondii

A screening platform for glioma growth and invasion using bioluminescence imaging

A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging

AAV-mediated local delivery of interferon-beta for the treatment of retinoblastoma in preclinical models

Aberrant tissue localization of fungus-specific CD4+ T cells in IL-10-deficient mice

Activation of Rap1 promotes prostate cancer metastasis

Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins

Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms

Advancing bioluminescence imaging technology for the evaluation of anticancer agents in the MDA-MB-435-HAL-Luc mammary fat pad and subrenal capsule tumor models

AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes

An acid-labile temperature-responsive sol-gel reversible polymer for enhanced gene delivery to the myocardium and skeletal muscle cells

An ancestral luciferase in the Malpighi tubules of a non-bioluminescent beetle!

An anti-vascular endothelial growth factor receptor 2/fetal liver kinase-1 Listeria monocytogenes anti-angiogenesis cancer vaccine for the treatment of primary and metastatic Her-2/neu+ breast tumors in a mouse model

Analysis of cancer stem cell metastasis in xenograft animal models

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli

Antitumoral efficacy of DNA nanoparticles in murine models of lung cancer and pulmonary metastasis

Apo2L/TRAIL inhibits tumor growth and bone destruction in a murine model of multiple myeloma

Bach1 modulates heme oxygenase-1 expression in the neonatal mouse lung

Biodegradable luminescent porous silicon nanoparticles for in vivo applications

Bioluminescence Imaging in Mouse Models Quantifies beta Cell Mass in the Pancreas and After Islet Transplantation

Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model

Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein

Bioluminescent Imaging of Intracranial Vestibular Schwannoma Xenografts in NOD/SCID Mice

Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness

Biomarker system for studying muscle, stem cells, and cancer in vivo

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP

Cancer targeted gene therapy of BikDD inhibits orthotopic lung cancer growth and improves long-term survival

Cetuximab retargeting of adenovirus via the epidermal growth factor receptor for treatment of intraperitoneal ovarian cancer

Characterization of hepatic sexual dimorphism in Alb-DsRed2 transgenic rats

Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis

Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastasis in a murine osteosarcoma model

CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy

Combination of viral oncolysis and tumor-specific immunity to control established tumors

Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors

Combining radiotherapy with APO010 in cancer treatment

Comparison of Gene-Transfer Efficiency in Human Embryonic Stem Cells

Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation

Comparison of subcutaneous and intraperitoneal injection of D-luciferin for in vivo bioluminescence imaging

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart

Concatenated multitype L2 fusion proteins as candidate prophylactic pan-human papillomavirus vaccines

Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats

Contribution of IRF-3 mediated IFNbeta production to DNA vaccine dependent cellular immune responses

CpxRA contributes to Xenorhabdus nematophila virulence through regulation of lrhA and modulation of insect immunity

Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution

De novo induction of genetically engineered brain tumors in mice using plasmid DNA

Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory

Depletion of cytosolic phospholipase A2 in bone marrow-derived macrophages protects against lung cancer progression and metastasis

Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors

Detection of functional haematopoietic stem cell niche using real-time imaging

Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation

Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung

Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescence Imaging

Directed evolution of adeno-associated virus to an infectious respiratory virus

Donor treatment with a multipegylated G-CSF maximizes graft-versus-leukemia effects

Dual Delivery of Placental Growth Factor and Vascular Endothelial Growth Factor from Poly(Hydroxyethyl Methacrylate-Co-Methyl Methacrylate) Microcapsules Containing Doubly Transfected Luciferase-Expressing L929 Cells

Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding

Effect of adeno-associated virus serotype and genomic structure on liver transduction and biodistribution in mice of both genders

Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer

Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis

Effects of cell number on teratoma formation by human embryonic stem cells

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma

Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects

Engineered measles virus as a novel oncolytic therapy against prostate cancer

Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model

Enhanced dermal wound neovascularization by targeted delivery of endothelial progenitor cells using an RGD-g-PLLA scaffold

Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells

Ethyl pyruvate administration inhibits hepatic tumor growth

Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy

Exposure to bile influences biofilm formation by Listeria monocytogenes

Extended-release PEG-luciferin allows for long-term imaging of firefly luciferase activity in vivo

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

Feedback regulation of cyclooxygenase-2 transcription ex vivo and in vivo

Flexible Filaments for in Vivo Imaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage

Fn14-TRAIL, a chimeric intercellular signal exchanger, attenuates experimental autoimmune encephalomyelitis

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

Genetic alteration of a bispecific ligand-directed toxin targeting human CD19 and CD22 receptors resulting in improved efficacy against systemic B cell malignancy

Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo

Heat-induced transcription of diphtheria toxin A or its variants, CRM176 and CRM197: implications for pancreatic cancer gene therapy

Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp

Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver

Hepatic siRNA delivery using recombinant human apolipoprotein A-I in mice

House dust mite allergen Der f 1 can induce the activation of latent TGF-beta via its protease activity

Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies

Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

Identification and metastatic potential of tumor-initiating cells in malignant rhabdoid tumor of the kidney

IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma

Imaging survival and function of transplanted cardiac resident stem cells

Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors

In vitro and in vivo bioluminescent quantification of viable stem cells in engineered constructs

In vivo bioluminescence imaging in an experimental mouse model for dendritic cell based immunotherapy against malignant glioma

In vivo bioluminescent imaging of Schwann cells in a poly(DL-lactide-epsilon-caprolactone) nerve guide

In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC)

In vivo imaging of murid herpesvirus-4 infection

In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

Increased fetal cell microchimerism in high grade breast carcinomas occurring during pregnancy

Induction of myelin protein zero by early growth response 2 through upstream and intragenic elements

Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer

Influences of capsule on cell shape and chain formation of wild-type and pcsB mutants of serotype 2 Streptococcus pneumoniae

Inhibition of nonneuronal alpha7-nicotinic receptor for lung cancer treatment

Intratracheal versus intravenous liposomal delivery of siRNA, antisense oligonucleotides and anticancer drug

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivo

Invariant natural killer T cell-natural killer cell interactions dictate transplantation outcome after alpha-galactosylceramide administration

Involvement of T helper type 17 and regulatory T cell activity in Citrobacter rodentium invasion and inflammatory damage

Keratin 7 promoter selectively targets transgene expression to normal and neoplastic pancreatic ductal cells in vitro and in vivo

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

KLF6-SV1 is a novel antiapoptotic protein that targets the BH3-only protein NOXA for degradation and whose inhibition extends survival in an ovarian cancer model

Lentiviruses with trastuzumab bound to their envelopes can target and kill prostate cancer cells

Lipocalin 2 promotes breast cancer progression

Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation

Long term non-invasive imaging of embryonic stem cells using reporter genes

Long-term transgene expression in the central nervous system using DNA nanoparticles

Low-amplitude ultrasound enhances hydrodynamic-based gene delivery to rat kidney

Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor

Measuring prions by bioluminescence imaging

Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression

Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression

Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery

Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment

Modulation of luciferase activity using high intensity focused ultrasound in combination with bioluminescence imaging, magnetic resonance imaging and histological analysis in muscle tissue

Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy

Molecular imaging of phosphorylation events for drug development

Monitoring NF-kappaB mediated chemokine transcription in tumorigenesis

Monitoring with a non-invasive bioluminescentin vivoimaging system of pleural metastasis of lung carcinoma

Multimodality imaging of TGF{beta} signaling in breast cancer metastases

Murid herpesvirus-4 lacking thymidine kinase reveals route-dependent requirements for host colonization

Murine Xenograft Model for Human Uterine Fibroids: An In Vivo Imaging Approach

Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice

Nasal-associated lymphoid tissue and olfactory epithelium as portals of entry for Burkholderia pseudomallei in murine melioidosis

Near-Infrared Fluorescence Labeled Anti-TAG-72 Monoclonal Antibodies for Tumor Imaging in Colorectal Cancer Xenograft Mice

NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model

Noninvasive Bioluminescent Imaging Demonstrates Long-Term Multilineage Engraftment of Ex Vivo-Expanded CD34-Selected Umbilical Cord Blood Cells

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

Nuclear factor-kappaB bioluminescence imaging-guided transcriptomic analysis for the assessment of host-biomaterial interaction in vivo

Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity

Oncolytic vaccinia therapy of squamous cell carcinoma

Optimising ultrasound-mediated gene transfer (sonoporation) in vitro and prolonged expression of a transgene in vivo: potential applications for gene therapy of cancer

Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients

Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model

PEI-PEG-Chitosan-Copolymer-Coated Iron Oxide Nanoparticles for Safe Gene Delivery: Synthesis, Complexation, and Transfection

Pharmacological profile of a novel H(2)S-releasing aspirin

Photoactivable bioluminescent probes for imaging luciferase activity

Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury

Pluripotency of mouse spermatogonial stem cells maintained by IGF-1- dependent pathway

PNAEmu can significantly reduce Burkitt's lymphoma tumor burden in a SCID mice model: cells dissemination similar to the human disease

Preclinical assessment of the treatment of second-stage african trypanosomiasis with cordycepin and deoxycoformycin

Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer

Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models

Preparation and non-invasive in-vivo imaging of anti-adhesion barriers with fluorescent polymeric marks

Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia

Quantification of mouse pulmonary cancer models by microcomputed tomography imaging

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

Real time noninvasive monitoring of contaminating bacteria in a soft tissue implant infection model

Real-time imaging of gene delivery and expression with DNA nanoparticle technologies

Real-time Visualisation of Human Prolactin Alternate Promoter Usage In vivo Using a Double-Transgenic Rat Model

Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications

Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells

Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 co-expressing mesenchymal stem cells

Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy

Revisiting Old Drugs as Novel Agents for Retinoblastoma: In vitro and In vivo Antitumor Activity of Cardenolides

Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion

Ring-Opening Metathesis Polymerization-Based Synthesis of ICG-Containing Amphiphilic Triblock Copolymers for in Vivo Tumor Imaging

RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells

Robust in vivo transduction of a genetically stable Epstein-Barr virus episome to hepatocytes in mice by a hybrid viral vector

Robust in vivo transduction of a genetically stable Epstein-Barr virus episome to hepatocytes in mice by a hybrid viral vector

Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model

Role of heparan sulfate in attachment to and infection of the murine female genital tract by human papillomavirus

Selective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain model

Selective uptake of multi-walled carbon nanotubes by tumor macrophages in a murine glioma model

Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase

SIGNR1-Negative Red Pulp Macrophages Protect against Acute Streptococcal Sepsis After Leishmania donovani-Induced Loss of Marginal Zone Macrophages

Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury

Systemic targeting of metastatic human breast tumor xenografts by Coxsackievirus A21

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections

Targeted delivery of siRNA against hepatitis C virus by apolipoprotein A-I-bound cationic liposomes

Targeted Disruption of the CXCL12/CXCR4 Axis Inhibits Osteolysis in a Murine Model of Myeloma-Associated Bone Loss

Targeted gene delivery to CD117-expressing cells in vivo with lentiviral vectors co-displaying stem cell factor and a fusogenic molecule

Targeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cells

Targeting anti-tumor DNA vaccines to dendritic cells via a short CD11c promoter sequence

Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth

Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer

The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts

The effect of cantharidins on leukemic stem cells

The effect of high intensity focused ultrasound on luciferase activity on two tumor cell lines in vitro, under the control of a CMV promoter

The effect of the nonionic block copolymer pluronic P85 on gene expression in mouse muscle and antigen-presenting cells

The gene transfection efficiency of a folate-PEI600-cyclodextrin nanopolymer

The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice

The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells

The major portal of entry of koi herpesvirus in cyprinus carpio is the skin

The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells

Tissue-specific homing and expansion of donor NK cells in allogeneic bone marrow transplantation

Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems

Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters

Treatment with demethylating agent, 5-aza-2'-deoxycytidine enhances therapeutic HPV DNA vaccine potency

Treatment with LL-37 peptide enhances antitumor effects induced by CpG oligodeoxynucleotides against ovarian cancer

Tumor vascular changes mediated by inhibition of oncogenic signaling

Use of biofluorescence imaging to compare the distribution of certolizumab pegol, adalimumab, and infliximab in the inflamed paws of mice with collagen-induced arthritis

Utilization of murine laparoscopy for continuous in-vivo assessment of the liver in multiple disease models

Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity

Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma

Visualizing human prostate cancer cells in mouse skeleton using bioconjugated near-infrared fluorescent quantum dots

2008

A bioluminescent HL-60 cell line to assay anti-leukaemia therapeutics under physiological conditions

A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence

A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding

A comparison between a time domain and continuous wave small animal optical imaging system

A daidzein-daunomycin conjugate improves the therapeutic response in an animal model of ovarian carcinoma

A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

A highly efficient protocol of generating and analyzing VZV ORF deletion mutants based on a newly developed luciferase VZV BAC system

A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes

A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging

A new transgenic mouse line to image chemically induced p53 activation in vivo

A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells. Laboratory investigation

A novel rat model for glioblastoma multiforme using a bioluminescent F98 cell line

A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis

A Pluripotency and Self-Renewal Program Controls the Expansion of Genetically Unstable Cancer Stem Cells in Pluripotent Stem Cell-Derived Tumors

A quantitative study of factors affecting in vivo bioluminescence imaging

A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method

Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii

Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier

ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction

Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer

Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma

Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer

Aggregation via the red, dry, and rough morphotype is not a virulence adaptation in Salmonella enterica serovar Typhimurium

alpha-Galactosylceramide enhances the protective and therapeutic effects of tumor cell based vaccines for ovarian tumors

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

An immunotolerant HER-2/neu transgenic mouse model of metastatic breast cancer

An in vivo mouse model for human prostate cancer metastasis

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection

Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival

Anti-glioblastoma effect of a recombinant bispecific cytotoxin cotargeting human IL-13 and EGF receptors in a mouse xenograft model

Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain

Antioxidant activity in the newborn brain: a luciferase mouse model

Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor

Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan

Antitumor effects of Mucin 1/sec involves the modulation of urokinase-type plasminogen activator and signal transducer and activator of transcription 1 expression in tumor cells

Applications of bioluminescence imaging to antiviral research and therapy: Multiple luciferase enzymes and quantitation

Applications of lentiviral vectors in noninvasive molecular imaging

Bacteriophage-amplified bioluminescent sensing of Escherichia coli O157:H7

Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects

Biochromoendoscopy: molecular imaging with capsule endoscopy for detection of adenomas of the GI tract

Bioimaging of dexamethasone and TGF beta-1 and its biological activities of chondrogenic differentiation in hydrogel constructs

Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells

Bioluminescence imaging of hematopoietic stem cell repopulation in murine models

Bioluminescence imaging of hepatitis B virus enhancer and promoter activities in mice

Bioluminescence imaging of hollow fibers in living animals: its application in monitoring molecular pathways

Bioluminescence imaging to evaluate infections and host response in vivo

Bioluminescence Imaging to monitor the in vivo Distribution of administered Mesenchymal Stem Cells in Acute Kidney Injury

Bioluminescence imaging to study the promoter activity of hla of Staphylococcus aureus in vitro and in vivo

Bioluminescence Imaging Visualizes Activation of Nuclear Factor-kappaB in Mouse Cardiac Transplantation

Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease

Bioluminescence: imaging modality for in vitro and in vivo gene expression

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis

Bioluminescent evaluation of the therapeutic effects of total body irradiation in a murine hematological malignancy model

Bioluminescent imaging of bacterial biofilm infections in vivo

Bioluminescent imaging of Trypanosoma cruzi infection

Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals

Bone marrow-derived myofibroblasts contribute functionally to scar formation after myocardial infarction

Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody

c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection

Cadherin-11 promotes the metastasis of prostate cancer cells to bone

Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53

CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses

Cell carriers to deliver oncolytic viruses to sites of myeloma tumor growth

Cell tracking with optical imaging

Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach

Characterization of endogenous plasmids from Lactobacillus salivarius UCC118

Chemical control of protein stability and function in living mice

Chemotherapy-induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction

Chimeric Receptor mRNA Transfection as a Tool to Generate Antineoplastic Lymphocytes

Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes

Co-expression of CYP27B1 enzyme with the 1.5kb CYP27B1 promoter-luciferase transgene in the mouse

Combination of treatment with death receptor 5-specific antibody with therapeutic HPV DNA vaccination generates enhanced therapeutic anti-tumor effects

Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells

Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors

Combined vascular endothelial growth factor receptor/epidermal growth factor receptor blockade with chemotherapy for treatment of local, uterine, and metastatic soft tissue sarcoma

Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation

Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities

Comparison of different adult stem cell types for treatment of myocardial ischemia

Comparison of Reporter Gene and Iron Particle Labeling for Tracking Fate of Human Embryonic Stem Cells and Differentiated Endothelial Cells in Living Subjects

Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis

Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas

Constitutive CXCL12 Expression Induces Anoikis in Colorectal Carcinoma Cells

Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin

Controlling Listeria monocytogenes in Cottage cheese through heterologous production of enterocin A by Lactococcus lactis

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia

Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses

Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity

Detection of Bacillus anthracis spore germination in vivo by bioluminescence imaging

Detection of protein-protein interactions in live cells and animals with split firefly luciferase protein fragment complementation

Development of a bicistronic vector for multimodality imaging of estrogen receptor activity in a breast cancer model: preliminary application

Development of a Dual-Luciferase Reporter System for In Vivo Visualization of MicroRNA Biogenesis and Posttranscriptional Regulation

Development of a luciferase-based reporter system to monitor Bifidobacterium breve UCC2003 persistence in mice

Development of bioluminescent Salmonella strains for use in food safety

Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection

Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy

Diet and abdominal autofluorescence detected by in vivo fluorescence imaging of living mice

Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells

Double Oxygen-sensing Vector System for Robust Hypoxia/Ischemia-regulated Gene Induction in Cardiac Muscle In Vitro and In Vivo

Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence

Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer

Dunning rat prostate adenocarcinomas and alternative splicing reporters: powerful tools to study epithelial plasticity in prostate tumors in vivo

Dynamics of Neutrophil Infiltration during Cutaneous Wound Healing and Infection Using Fluorescence Imaging

Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging

Eastern and Venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis

Effect of mouse VEGF(164) on the viability of hydroxyethyl methacrylate-methyl methacrylate-microencapsulated cells in vivo: Bioluminescence imaging

Effective CpG immunotherapy of breast carcinoma prevents but fails to eradicate established brain metastasis

Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging

Efficient Inhibition of wear debris-induced inflammation by locally delivered siRNA

Embryonic origin and Hox status determine progenitor cell fate during adult bone regeneration

Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling

Endotoxin-Induced Proteolytic Reduction in Hepatic Growth Hormone Receptor: A Novel Mechanism for GH Insensitivity

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin

Enhancing bile tolerance improves survival and persistence of Bifidobacterium and Lactococcus in the murine gastrointestinal tract

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

Escape from suppression: tumor-specific effector cells outcompete regulatory T cells following stem-cell transplantation

Escherichia coli Nissle 1917 Facilitates Tumor Detection by Positron Emission Tomography and Optical Imaging

Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT

Evaluation of gene promoters for liver expression by hydrodynamic gene transfer

Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma

Evidence for a superoxide permeability pathway in endosomal membranes

Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic

Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation

Extracts of dietary plants are efficient modulators of nuclear factor kappa B

First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells

Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery

Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice

Functional interaction of regulatory factors with the Pgc-1{alpha} promoter in response to exercise by in vivo imaging

Gene silencing in mammalian cells with light-activated antisense agents

Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging

Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas

Glucosamine-bound near-infrared fluorescent probes with lysosomal specificity for breast tumor imaging

Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention

Glutathione S-transferase Pi mediates proliferation of androgen-independent prostate cancer cells

Hepatic glucose sensing via the CREB coactivator CRTC2

High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents

Histoplasma capsulatum yeast phase-specific protein Yps3p induces Toll-like receptor 2 signaling

Hyperthermia induced targeting of thermosensitive gene carriers to tumors

Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype

Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling

IFN-beta sensitizes neuroblastoma to the antitumor activity of temozolomide by modulating O6-methylguanine DNA methyltransferase expression

Imagable 4T1 model for the study of late stage breast cancer

Image-based evaluation of the molecular events underlying HC11 mammary epithelial cell differentiation

Image-guided enzyme/prodrug cancer therapy

Imaging characteristics of zinc sulfide shell, cadmium telluride core quantum dots

Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe

Imaging spontaneous tumorigenesis: Inflammation precedes development of peripheral NK tumors

Imaging stem cell implant for cellular-based therapies

Imaging target mRNA and siRNA-mediated gene silencing in vivo with ribozyme-based reporters

Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts

Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers

Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation

Improved QD-BRET conjugates for detection and imaging

In vivo analysis of heat-shock-protein-70 induction following pulsed laser irradiation in a transgenic reporter mouse

In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy

In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation

In Vivo Imaging of miR-221 Biogenesis in Papillary Thyroid Carcinoma

In vivo imaging of NF-kappaB activity during Escherichia coli-induced mammary gland infection

In vivo optical imaging of neurogenesis: watching new neurons in the intact brain

In vivo time-dependent gene expression of cationic lipid-based emulsion as a stable and biocompatible non-viral gene carrier

In-vivo optical imaging of hsp70 expression to assess collateral tissue damage associated with infrared laser ablation of skin

Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase

Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Inhibition of heme oxygenase activity in newborn mice by azalanstat

Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-specific RNA Aptamer

Inhibition of repair of radiation-induced DNA damage enhances gene expression from replication-defective adenoviral vectors

Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases

Inhibition of tissue factor signaling suppresses tumor growth

Inhibition of toll-like receptor signaling in primary murine microglia

Integrating the biological characteristics of oncolytic viruses and immune cells can optimize therapeutic benefits of cell-based delivery

Interstitial inflammatory lesions of the pulmonary allograft: a retrospective analysis of 2697 transbronchial biopsies

Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX

Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models

Invincible, but not invisible: imaging approaches toward in vivo detection of cancer stem cells

Involvement of Cyr61 in growth, migration, and metastasis of prostate cancer cells

KGF-1 for wound healing in animal models

Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis

Lactococcus lactis-expressing listeriolysin O (LLO) provides protection and specific CD8(+) T cells against Listeria monocytogenes in the murine infection model

Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression

Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells

Lentivirus vector can be readministered to nasal epithelia without blocking immune responses

Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes

Live imaging of neuroinflammation reveals sex and estrogen effects on astrocyte response to ischemic injury

Liver-directed gene therapy using the sleeping beauty transposon system

Local delivery of gene vectors from bare-metal stents by use of a biodegradable synthetic complex inhibits in-stent restenosis in rat carotid arteries

Longitudinal Non-invasive Monitoring of Transcription Factor Activation in Cardiovascular Regulatory Nuclei Using Bioluminescence Imaging

Low-dose radiation enhances therapeutic HPV DNA vaccination in tumor-bearing hosts

Low-intensity ultrasound and microbubbles enhance the antitumor effect of cisplatin

LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

Macrophage mannose receptor on lymphatics controls cell trafficking

Matrix metalloproteinase-1 promotes prostate tumor growth and metastasis

Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed

Merlin is a potent inhibitor of glioma growth

Metastatic cancer cells with macrophage properties: evidence from a new murine tumor model

Microbial colonization of an in vitro model of a tissue engineered human skin equivalent--a novel approach

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen

Molecular and cellular MR imaging: potentials and challenges for neurological applications

Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice

Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1beta

Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects

Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer

Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis

Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects

Monitoring the efficacy of adoptively transferred prostate cancer-targeted human T lymphocytes with PET and bioluminescence imaging

Morphine and propranolol co-administration impair consolidation of Y-maze spatial recognition memory

Morphine induces defects in early response of alveolar macrophages to Streptococcus pneumoniae by modulating TLR9-NF-kappa B signaling

Morphological aspects of surgical meshes as a risk factor for bacterial colonization

Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells

Multimodal imaging and treatment of bone metastasis

Murine maternal cell microchimerism: analysis using real-time PCR and in vivo imaging

Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

Nanoconjugate based on polymalic acid for tumor targeting

Near-infrared fluorescent labeled peptosome for application to cancer imaging

Neural progenitor cell-mediated delivery of interferon beta improves neuroblastoma response to cyclophosphamide

Neuropilin-2-mediated tumor growth and angiogenesis in pancreatic adenocarcinoma

Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer

Noninvasive and quantitative monitoring of adult neuronal stem cell migration in mouse brain using bioluminescence imaging

Noninvasive assessment of E2F-1-mediated transcriptional regulation in vivo

Noninvasive bioluminescence imaging in small animals

Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy

Noninvasive in vivo imaging of protein kinase a activity

Noninvasive Real-time Imaging of Tumors and Metastases Using Tumor-targeting Light-emitting Escherichia coli

Nonviral nanoscale-based delivery of antisense oligonucleotides targeted to hypoxia-inducible factor 1 alpha enhances the efficacy of chemotherapy in drug-resistant tumor

Nuclear factor-kappaB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells

Oncolytic adenoviruses for cancer gene therapy

Oncolytic vaccinia virotherapy of anaplastic thyroid cancer in vivo

Optical imaging: current applications and future directions

Ossicle and vossicle implant model systems

Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects

Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

Oxycodone-induced analgesic effects in a bone cancer pain model in mice

p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts

Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation

PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

Periocular triamcinolone enhances intraocular gene expression after delivery by adenovirus

Persistent gammaherpesvirus replication and dynamic interaction with the host in vivo

PET imaging of T cells derived from umbilical cord blood

Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation

Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery

Potent systemic anticancer activity of adenovirally expressed EGFR-selective TRAIL fusion protein

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways

Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging

Pretreatment with cisplatin enhances E7-specific CD8+ T-Cell-mediated antitumor immunity induced by DNA vaccination

Prevention of airway inflammation with topical cream containing imiquimod and small interfering RNA for natriuretic peptide receptor

Profound but dysfunctional lymphangiogenesis via vascular endothelial growth factor ligands from CD11b+ macrophages in advanced ovarian cancer

Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation

Prolonged microglial cell activation and lymphocyte infiltration following experimental herpes encephalitis

Prolonging islet allograft survival using in vivo bioluminescence imaging to guide timing of antilymphocyte serum treatment of rejection

Prompt Assessment of WST11-VTP Outcome Using Luciferase Transfected Tumors Enables Second Treatment and Increase in Overall Therapeutic Rate

Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2

Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation

PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel

Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella

Quantitative bioluminescence imaging of tumor-targeting bacteria in living animals

Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity

Quantum dot probes for bacteria distinguish Escherichia coli mutants and permit in vivo imaging

Quorum-sensing signals in the microbial community of the cabbage white butterfly larval midgut

Radiation-guided P-selectin antibody targeted to lung cancer

Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: implications for sodium iodide symporter gene therapy

Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10

RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis

Real-time in vivo monitoring of viable stem cells implanted on biocompatible scaffolds

Receptor targeted polymers, dendrimers, liposomes: which nanocarrier is the most efficient for tumor-specific treatment and imaging?

Recruitment of host progenitor cells in rat liver transplants

Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice

Relaxin treatment of solid tumors: effects on electric field-mediated gene delivery

Retargeting of Human T Cells to Tumor-Associated MUC1: The Evolution of a Chimeric Antigen Receptor

Role of IL-2 secreted by PADRE-specific CD4+ T cells in enhancing E7-specific CD8+ T-cell immune responses

Role of NleH, a type III secreted effector from attaching and effacing pathogens, in colonization of the bovine, ovine, and murine gut

Seeding and propagation of untransformed mouse mammary cells in the lung

Self-renewal and expansion of single transplanted muscle stem cells

Short hairpin RNA interference therapy for ischemic heart disease

Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

Site-directed mutagenesis of firefly luciferase: implication of conserved residue(s) in bioluminescence emission spectra among firefly luciferases

Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

Stability study of unmodified siRNA and relevance to clinical use

Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation

Superoxide dismutase attenuates hyperoxia-induced interleukin-8 induction via AP-1

Sustained (rh)VEGF(165) release from a sprayed fibrin biomatrix induces angiogenesis, up-regulation of endogenous VEGF-R2, and reduces ischemic flap necrosis

Sustained release of drugs dispersed in polymer nanoparticles

Synergistic tumoricidal effect of combined hMUC1 vaccination and hNIS radioiodine gene therapy

Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes

Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis

Systemically transplanted bone marrow stromal cells contributing to bone tissue regeneration

TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer

Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome

Targeting mRNA stability arrests inflammatory bone loss

Targeting of the CNS in MPS-IH using a nonviral transferrin-alpha-L-iduronidase fusion gene product

Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

Temporal and spatial distribution of Toxoplasma gondii differentiation into Bradyzoites and tissue cyst formation in vivo

The ARF tumor suppressor can promote the progression of some tumors

The chemokine receptor CXCR6 and its ligand CXCL16 are expressed in carcinomas and inhibit proliferation

The effect of high intensity focused ultrasound treatment on metastases in a murine melanoma model

The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings

The influence of hypoxia on bioluminescence in luciferase-transfected gliosarcoma tumor cells in vitro

The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium

The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread

Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer

Tissue engineering using autologous microcirculatory beds as vascularized bioscaffolds

Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice

TLR3 Increases Disease Morbidity and Mortality from Vaccinia Infection

TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN

Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Tools for functional postgenomic analysis of listeria monocytogenes

Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond

Transcriptional modulation using HDACi depsipeptide promotes immune cell-mediated tumor destruction of murine B16 melanoma

Transcriptional Profiling of Human Mesenchymal Stem Cells Transduced with Reporter Genes for Imaging

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

TRE-dependent transcription activation by JDP2-CHOP10 association

TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles

Tumor tissue characterization evaluating the luciferase activity under the control of a hsp70 promoter and MR imaging in three tumor cell lines

Tumor-targeted delivery of siRNA by self-assembled nanoparticles

Tumor-targeting prodrug-activating bacteria for cancer therapy

Tumorigenic potential and disease manifestations of malignant B-cell variants differing in their fibronectin adhesiveness

Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis

Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth

Viral vector-based prime-boost immunization regimens: a possible involvement of T-cell competition

Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes

Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer

Whole animal in vivo imaging after transient, nonviral gene delivery to the rat central nervous system

Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo

Zoledronic acid decreased osteolysis but not bone metastasis in a nude mouse model of canine prostate cancer with mixed bone lesions

2007

[Bioluminescence: the potential of a non-invasive bio-optical imaging technique and improvement of animal research]

[Bioluminescent imaging to monitor tumor progression and metastasis in live animal.]

A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancer

A new technique for physiodesis using photodynamic therapy

A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis

A novel method for imaging in vivo degradation of poly(l-glutamic Acid), a biodegradable drug carrier

A perivascular niche for brain tumor stem cells

A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

A universal technology for monitoring G-protein-coupled receptor activation in vitro and noninvasively in live animals

ABCG2/BCRP Expression Modulates D-Luciferin Based Bioluminescence Imaging

Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter

Advances in optical imaging and novel model systems for cancer metastasis research

An imaging biomarker of early treatment response in prostate cancer that has metastasized to the bone

An Orthotopic Skull Base Model of Malignant Meningioma

Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis

Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults

Antibody targeting of the insulin-like growth factor I receptor enhances the anti-tumor response of multiple myeloma to chemotherapy through inhibition of tumor proliferation and angiogenesis

Antitumor activity of novel indirubin derivatives in rat tumor model

Applications of bioluminescence imaging to the study of infectious diseases

Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors

Bioluminescence imaging for assessment and normalization in transfected cell arrays

Bioluminescent imaging of hepatocellular carcinoma in live mice

Bioluminescent mammalian cells grown in sponge matrices to monitor immune rejection

Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays

Bone marrow-derived myofibroblasts contribute functionally to scar formation after myocardial infarction

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

Bradyzoite-specific surface antigen SRS9 plays a role in maintaining Toxoplasma gondii persistence in the brain and in host control of parasite replication in the intestine

Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(beta-L-malic acid)

Breast cancer metastasis to bone: evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice

Bringing bioluminescence into the picture

Broad host range fluorescence and bioluminescence expression vectors for Gram-negative bacteria

Carrier Cell-based Delivery of an Oncolytic Virus Circumvents Antiviral Immunity

CD101 Surface Expression Discriminates Potency Among Murine FoxP3+ Regulatory T Cells

CD4+CD25+ regulatory T-cell-inactivation in combination with adenovirus vaccines enhances T-cell responses and protects mice from tumor challenge

Cell Cycle Dependent and Schedule-Dependent Antitumor Effects of Sorafenib Combined with Radiation

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy

Chitosan solution enhances the immunoadjuvant properties of GM-CSF

Chronic exposure to 12-O-tetradecanoylphorbol-13-acetate represses sod2 induction in vivo: the negative role of p50

Combinatorial Library Screening for Developing an Improved Split-Firefly Luciferase Fragment-Assisted Complementation System for Studying Protein-Protein Interactions

Combining adoptive cellular and immunocytokine therapies to improve treatment of B-lineage malignancy

Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain

Comparison of several linear fluorophore- and quencher-conjugated oligomer duplexes for stability, fluorescence quenching, and kinetics in vitro and in vivo in mice

Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects

Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria

Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature

Control of human mesothelin-expressing tumors by DNA vaccines

Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8(+) T cells

COX-2 involvement in breast cancer metastasis to bone

Creation and Characterization of a Doxycycline-Inducible Mouse Model of Thyroid-Targeted RET/PTC1 Oncogene and Luciferase Reporter Gene Coexpression

CREB is a critical regulator of normal hematopoiesis and leukemogenesis

Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products

Current State of Imaging Protein-Protein Interactions In Vivo With Genetically Encoded Reporters

CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway

Delivery and Inhibition of Reporter Genes by Small Interfering RNAs in a Mouse Skin Model

Demethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer

Derivation of engraftable skeletal myoblasts from human embryonic stem cells

Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping

Development of gelatin nanoparticles with biotinylated EGF conjugation for lung cancer targeting

Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo

Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease

Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease

Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease

Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion

Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transfer

Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation

Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells

Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host

Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2m(null) mice

Failure of TLR4-driven NF-kappa B activation to stimulate virus replication in models of HIV type 1 activation

Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model

Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imaging

Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored beta-glucuronidase

Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome system

Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function

Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts

Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis

Heparan sulfate binding can contribute to the neurovirulence of neuroadapted and nonneuroadapted Sindbis viruses

Herpes Simplex Virus Thymidine Kinase-Mediated Suicide Gene Therapy Using Nano/Microbubbles and Ultrasound

Heterozygosity of genes on the sex chromosome regulates Candida albicans virulence

Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease

Hypersusceptibility to invasive pneumococcal infection in experimental sickle cell disease involves platelet-activating factor receptor

IFN-gamma and Fas ligand are required for graft-versus-tumor activity against renal cell carcinoma in the absence of lethal graft-versus-host disease

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

Image-guided analyses reveal that non-CD4 splenocytes contribute to CD4+ T cell-mediated inflammation leading to islet destruction by altering their local function and not systemic trafficking patterns

Imaging CD8+ T cell dynamics in vivo using a transgenic luciferase reporter

Imaging of hypoxia-driven gene expression in an orthotopic liver tumor model

Imaging of Mesenchymal Stem Cell Transplant by Bioluminescence and PET

Imaging the Modulation of Adenoviral Kinetics and Biodistribution for Cancer Gene Therapy

Immune Response to Firefly Luciferase as a Naked DNA

Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro

In situ pulmonary localization of air pollution particle-induced oxidative stress

In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene

In vivo bioluminescence visualization of antitumor effects by human MUC1 vaccination

In vivo electroporation enhances the immunogenicity of hepatitis C virus nonstructural 3/4A DNA by increased local DNA uptake, protein expression, inflammation, and infiltration of CD3+ T cells

In vivo fluorescence imaging of the reticuloendothelial system using quantum dots in combination with bioluminescent tumour monitoring

In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival

In vivo imaging in experimental preclinical tumor research--a review

In vivo imaging of hepcidin promoter stimulation by iron and inflammation

In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles

In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts

Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza

Influenza A virus PB1-F2: a small protein with a big punch

Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis

Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2

Intravascular administration of tumor tropic neural progenitor cells permits targeted delivery of interferon-beta and restricts tumor growth in a murine model of disseminated neuroblastoma

Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells

Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of Expression

Live imaging of Smad2/3 signaling in mouse skin wound healing

Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis

Local radiotherapy induces homing of hematopoietic stem cells to the irradiated bone marrow

Localized recrudescence of Toxoplasma infections in the central nervous system of immunocompromised mice assessed by in vivo bioluminescence imaging

Lung-directed gene therapy in mice using the nonviral Sleeping Beauty transposon system

Macrophage-mediated colocalization of quantum dots in experimental glioma

Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis

Messenger RNA as a Source of Transposase for Sleeping Beauty Transposon-mediated Correction of Hereditary Tyrosinemia Type I

Methods for imaging cell fates in hematopoiesis

MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment

Molecular Imaging of Bone Marrow Mononuclear Cell Homing and Engraftment in Ischemic Myocardium

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation

Monitoring of disease progression by bioluminescence imaging and magnetic resonance imaging in an animal model of hematologic malignancy

Monitoring the trafficking of adoptively transferred antigen- specific CD8-positive T cells in vivo, using noninvasive luminescence imaging

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence

Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression

Multimodality imaging: novel pharmacological applications of reporter systems

Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel

Murine alveolar macrophages limit replication of vaccinia virus

Neural progenitor cell transplantation and imaging in a large animal model

Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia

Non-capsulated toxinogenic Bacillus anthracis present a specific growth and dissemination pattern in naive and PA-immune mice

Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model

Non-invasive fluorescent imaging of gliosis in transgenic mice for profiling developmental neurotoxicity

Noninvasive molecular imaging sheds light on the synergy between 5-fluorouracil and TRAIL/Apo2L for cancer therapy

Noninvasive nuclear factor-kappaB bioluminescence imaging for the assessment of host-biomaterial interaction in transgenic mice

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes

Novel strategy to prevent otitis media caused by colonizing Streptococcus pneumoniae

Optical antisense imaging of tumor with fluorescent DNA duplexes

Optical bioluminescence imaging of human ES cell progeny in the rodent CNS

Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody

Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validation

Optical pretargeting of tumor with fluorescent MORF oligomers

Optimization of Topical Therapy for Leishmania major Localized Cutaneous Leishmaniasis Using a Reliable C57BL/6 Model

Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation

Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma

Potency of siRNA versus shRNA mediated knockdown in vivo

Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo

Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cells

Prolonged In Vivo Gene Silencing by Electroporation-Mediated Plasmid Delivery of Small Interfering RNA

Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method

Quantum dots are phagocytized by macrophages and colocalize with experimental gliomas

Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer models

Rapid bactericidal activity of daptomycin against methicillin-resistant and methicillin-susceptible Staphylococcus aureus peritonitis in mice as measured with bioluminescent bacteria

Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticles

Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

Regression of experimental medulloblastoma following transfer of HER2-specific T cells

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

Restricted tissue tropism and acquired resistance to Sindbis viral vector expression in the absence of innate and adaptive immunity

Sarcoma derived from cultured mesenchymal stem cells

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma

Sine-wave current for efficient and safe in vivo gene transfer

Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis

Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells

Stem cell transplantation: the lung barrier

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo

Switching on the lights for gene therapy

Synthetic PEGylated Glycoproteins and Their Utility in Gene Delivery

Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I

T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection

Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammation

Targeted inflammation during oncolytic virus therapy severely compromises tumor blood flow

Targeted Proapoptotic Anticancer Drug Delivery System

The epididymal fat pad as a transplant site for minimal islet mass

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia

The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility

The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling

The PilA protein of non-typeable Haemophilus influenzae plays a role in biofilm formation, adherence to epithelial cells and colonization of the mammalian upper respiratory tract

The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesis

The type III TGF-beta receptor suppresses breast cancer progression

Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model

Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo

Three-dimensional reconstruction of in vivo bioluminescent sources based on multispectral imaging

Topoisomerase Inhibition Accelerates Gene Expression after Adeno-associated Virus-mediated Gene Transfer to the Mammalian Heart

Toxoplasma gondii: Inconsistent dissemination patterns following oral infection in mice

Tracking the migration of dendritic cells by in vivo optical imaging

Treatment of anaplastic thyroid carcinoma in vitro with a mutant vaccinia virus

Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment

Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci

Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells

Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis

Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus

Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirus

Vaccinia virus preferentially infects and controls human and murine ovarian tumors in mice

Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth

Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model

Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells

2006

A Comparison of Antiangiogenic Therapies for the Prevention of Liver Metastases

A Novel Method of Monitoring Response to Islet Transplantation: Bioluminescent Imaging of an NF-kB Transgenic Mouse Model. [Article]

A Novel Noninvasive Model of Endometriosis for Monitoring the Efficacy of Antiangiogenic Therapy

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6

A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo

Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine

Activation of iCaspase-9 in neovessels inhibits oral tumor progression

Activity of the Adenoviral E1A Deletion Mutant dl922-947 in Ovarian Cancer: Comparison with E1A Wild-type Viruses, Bioluminescence Monitoring, and Intraperitoneal Delivery in Icodextrin

Adenoviral Human BCL-2 Transgene Expression Attenuates Early Donor Cell Death After Cardiomyoblast Transplantation Into Ischemic Rat Hearts

Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation

An attenuated Salmonella oral DNA vaccine prevents the growth of hepatocellular carcinoma and colon cancer that express alpha-fetoprotein

An intramolecular folding sensor for imaging estrogen receptor-ligand interactions

Antitumor activity of IFN-lambda in murine tumor models

Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model

Assessing laser-tissue damage with bioluminescent imaging

Bacterial sinusitis and otitis media following influenza virus infection in ferrets

Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors

Bioluminescence Imaging of Live Infected Salmonids Reveals that the Fin Bases Are the Major Portal of Entry for Novirhabdovirus

Bioluminescence Imaging of Systemic Tumor Targeting Using a Prostate-Specific Lentiviral Vector

Bioluminescent quantum dots

Caught in the act: in vivo molecular imaging of the transcription factor NF-kappaB after myocardial infarction

Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.

CG0070, a Conditionally Replicating Granulocyte Macrophage Colony-Stimulating Factor-Armed Oncolytic Adenovirus for the Treatment of Bladder Cancer

Chemokines, chemokine receptors, and cancer metastasis

CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3-Expressing Orthotopic Multiple Myeloma Model in Mice

Collagen Matrices Enhance Survival of Transplanted Cardiomyoblasts and Contribute to Functional Improvement of Ischemic Rat Hearts

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon

Creating self-illuminating quantum dot conjugates

Development of bioluminescent Edwardsiella ictaluri for noninvasive disease monitoring

Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies

Differential Biodistribution of Adenoviral Vector In Vivo as Monitored by Bioluminescence Imaging and Quantitative Polymerase Chain Reaction

Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing

Efficacy of zoledronate against neuroblastoma

Efficient in vivo knock-down of estrogen receptor alpha: application of recombinant adenovirus vectors for delivery of short hairpin RNA.

Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins

Endostatin-Cytosine Deaminase Fusion Protein Suppresses Tumor Growth by Targeting Neovascular Endothelial Cells

Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study

Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration

Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: impact of application routes and delivery with dendritic cells

Evaluation of T cells as carriers for systemic measles virotherapy in the presence of antiviral antibodies

Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants

EZC-Prostate Models Offer High Sensitivity and Specificity for Noninvasive Imaging of Prostate Cancer Progression and Androgen Receptor Action

Fetal Gene Transfer Using Lentiviral Vectors: In Vivo Detection of Gene Expression by microPET and Optical Imaging in Fetal and Infant Monkeys

From the Cover: Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production

Functions of CXCL12 and CXCR4 in breast cancer

Gene transfer to rabbit retina with electron avalanche transfection

Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion

Genetically encoded optical probe for detecting release of proteins from mitochondria toward cytosol in living cells and mammals

Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity

Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity

High intensity focused ultrasound-induced gene activation in solid tumors

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells

Imaging Cyclooxygenase-2 (Cox-2) Gene Expression in Living Animals with a Luciferase Knock-in Reporter Gene

Imaging mitogen-activated protein kinase function in xenograft models of prostate cancer

In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animals

In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animals

In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium

In Vivo Bioluminescence Imaging of the Murine Pathogen Citrobacter rodentium

In Vivo Bioluminescence Imaging of Transplanted Islets and Early Detection of Graft Rejection. [Article]

In vivo electroporation and ubiquitin promoter - a protocol for sustained gene expression in the lung

In Vivo Imaging of Hepatic Growth Hormone Signaling

In vivo imaging using bioluminescence: a tool for probing graft-versus-host disease

In vivo luminescent imaging of cyclosporin A-mediated cancer progression in rats

In vivo molecular imaging of adenoviral versus lentiviral gene therapy in two bone formation models

In vivo monitoring of DNA vaccine gene expression using firefly luciferase as a naked DNA

In vivo monitoring of pancreatic beta-cells in a transgenic mouse model

In Vivo Near-Infrared Fluorescence Imaging of Integrin alpha V beta 3 in an Orthotopic Glioblastoma Model

In vivo testing of Renilla luciferase substrate analogs in an orthotopic murine model of human glioblastoma

In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, and Migration After Cardiac Delivery

Induced biliary excretion of Listeria monocytogenes

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

Involvement of IL-8 in COX-2-Mediated Bone Metastases from Breast Cancer

Labelling of human adipose-derived stem cells for non-invasive in vivo cell tracking

Luciferin Derivatives for Enhanced in Vitro and in Vivo Bioluminescence Assays

Luminescent imaging of [beta]-galactosidase activity in living subjects using sequential reporter-enzyme luminescence

Matrix Metalloproteinase-9 from Bone Marrow-Derived Cells Contributes to Survival but not Growth of Tumor Cells in the Lung Microenvironment

Monitoring of bactericidal action of laser by in vivo imaging of bioluminescent E. coli in a cutaneous wound infection

Near-Infrared Fluorescence Imaging of Tumor Integrin alpha(v)beta (3) Expression with Cy7-Labeled RGD Multimers

Near-Infrared Fluorescent Deoxyglucose Analogue for Tumor Optical Imaging in Cell Culture and Living Mice

New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograft

NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivo

NK and CD4 cells collaborate to protect against melanoma tumor formation in the brain

Non-invasive bioluminescence imaging for monitoring herpes simplex virus type 1 hematogenous infection

Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect

Noninvasive Bioluminescence Imaging of Normal and Spontaneously Transformed Prostate Tissue in Mice

Noninvasive Evaluation of Immunosuppressive Drug Efficacy on Acute Donor Cell Survival

Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer

Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice

Noninvasive Monitoring of Long-Term Lentiviral Vector-Mediated Gene Expression in Rodent Brain with Bioluminescence Imaging

Noninvasive Optical Tracking of Red Fluorescent ProteinExpressing Cancer Cells in a Model of Metastatic Breast Cancer

Novel luciferase reporter system for in vitro and organ-specific monitoring of differential gene expression in Listeria monocytogenes

Novel Robust Hepatitis C Virus Mouse Efficacy Model

Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells

p73 or p53 Directly Regulates Human p53 Transcription to Maintain Cell Cycle Checkpoints

PGC-1alpha controls hepatitis B virus through nutritional signals

Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells

Quantifying the Activity of Adenoviral E1A CR2 Deletion Mutants Using Renilla Luciferase Bioluminescence and 3'-Deoxy-3'-[18F]Fluorothymidine Positron Emission Tomography Imaging

Quantitative bioluminescence imaging of transgene expression in vivo

Quantitative bioluminescence imaging of transgene expression in vivo

Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta

Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice

Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice

RNA as a Source of Transposase for Sleeping Beauty-Mediated Gene Insertion and Expression in Somatic Cells and Tissues

Sarcoma Derived from Cultured Mesenchymal Stem Cells

Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imaging

Self-illuminating quantum dot conjugates for in vivo imaging

Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts

Spatiotemporal expression of heme oxygenase-1 detected by in vivo bioluminescence after hepatic ischemia in HO-1/luc mice

Spectral Unmixing of Multicolored Bioluminescence Emitted from Heterogeneous Biological Sources

Synergistic Antitumor Effects of Immune Cell-Viral Biotherapy

Systemic effects of orally-administered zinc and tin (IV) metalloporphyrins on heme oxygenase expression in mice

T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells

The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude mice

The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity

The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor {beta}-Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells

Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo

Transgenic mouse for conditional, tissue-specific Cox-2 overexpression

Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of Antiandrogens

Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice

Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy

Tumor-selective gene expression in a hepatic metastasis model after locoregional delivery of a replication-competent retrovirus vector

Tumorigenic conversion of primary human esophageal epithelial cells using oncogene combinations in the absence of exogenous Ras

Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homing

Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer

Visualization of antigen-specific T cell in living arthritic mice

Visualization of Telomerase Reverse Transcriptase (hTERT) Promoter Activity Using a Trimodality Fusion Reporter Construct

Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase gene

2005

A luciferase transgenic mouse model: visualization of prostate development and its androgen responsiveness in live animals

A mutation in the sap operon attenuates survival of nontypeable Haemophilus influenzae in a chinchilla model of otitis media

A Novel Method for Viral Gene Delivery in Solid Tumors

A quantitative high-throughput chemotaxis assay using bioluminescent reporter cells

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression

A third-generation bisphosphonate, minodronic acid (YM529), augments the interferon alpha/beta-mediated inhibition of renal cell cancer cell growth both in vitro and in vivo

Adeno-Associated Virus Vector-Mediated Systemic Delivery of IFN-{beta} Combined with Low-Dose Cyclophosphamide Affects Tumor Regression in Murine Neuroblastoma Models

Adoptive transfer of mast cells does not enhance the impaired survival of KitW/KitW-v mice in a model of low dose intraperitoneal infection with bioluminescent Salmonella typhimurium

Advances in imaging mouse tumour models in vivo

Apigenin decreases hemin-mediated heme oxygenase-1 induction

Assessing Tumor Growth and Distribution in a Model of Prostate Cancer Metastasis using Bioluminescence Imaging

Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging

Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains

Bioluminescence imaging of vaccinia virus: Effects of interferon on viral replication and spread

Bioluminescence regenerative cycle (BRC) system: theoretical considerations for nucleic acid quantification assays

Bioluminescence technology for imaging cell proliferation

Bioluminescent human breast cancer cell lines that permit rapid and sensitive

Bioluminescent imaging of melanoma in live mice

Bioluminescent Imaging of Ubiquitin Ligase Activity: Measuring Cdk2 Activity In Vivo Through Changes in p27 Turnover

Biophotonic imaging in HO-1.luc transgenic mice: Real-time demonstration of gender-specific chloroform induced renal toxicity

BMP gene delivery for alveolar bone engineering at dental implant defects

Bone turnover mediates preferential localization of prostate cancer in the skeleton

CCR2 is required for CD8-induced graft-versus-host disease

CD36 is a sensor of diacylglycerides

Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Chemical and genetic sensors in biomedical research

Combinatorial Antiangiogenic Gene Therapy by Nonviral Gene Transfer Using the Sleeping Beauty Transposon Causes Tumor Regression and Improves Survival in Mice Bearing Intracranial Human Glioblastoma

Development of a chinchilla model to allow direct, continuous, biophotonic imaging of bioluminescent nontypeable Haemophilus influenzae during experimental otitis media

Development of a Conditional In vivo Model to Evaluate the Efficacy of Small Molecule Inhibitors for the Treatment of Raf-Transformed Hematopoietic Cells

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

Dynamic Gene Expression After Systemic Delivery of Plasmid DNA as Determined by In Vivo Bioluminescence Imaging

Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo

Electrohydrodynamic Comminution: A Novel Technique for the Aerosolisation of Plasmid DNA

Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo

Engineering vascularized skeletal muscle tissue

Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1

Enhancement of Cancer Radiation Therapy by Use of Adenovirus-Mediated Secretable Glucose-Regulated Protein 94/gp96 Expression

Ex Vivo Expanded Dendritic Cells Home to T-Cell Zones of Lymphoid Organs and Survive in Vivo after Allogeneic Bone Marrow Transplantation

Firefly luciferase enzyme fragment complementation for imaging in cells and living animals

Functionality of Androgen Receptor-Based Gene Expression Imaging in Hormone Refractory Prostate Cancer

Gene silencing in rat-liver and limb grafts by rapid injection of small interference RNA

Genes that mediate breast cancer metastasis to lung

Genetically Encoded Stress Indicator for Noninvasively Imaging Endogenous Corticosterone in Living Mice

Global Analysis of Smad2/3-Dependent TGF-{beta} Signaling in Living Mice Reveals Prominent Tissue-Specific Responses to Injury

H2 relaxin overexpression increases in vivo prostate xenograft tumor growth and angiogenesis

Herpesvirus saimiri-based vector biodistribution using noninvasive optical imaging

High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice

Highly specific expression of luciferase gene in lungs of naIve nude mice directed by prostate-specific antigen promoter

Image-Guided Cardiac Cell Delivery Using High-Resolution Small-Animal Ultrasound

In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets

In vivo Assessment of RAS-Dependent Maintenance of Tumor Angiogenesis by Real-time Magnetic Resonance Imaging

In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury

In vivo imaging of retinoic acid receptor beta2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells

In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs

In vivo RNA Interference-Mediated Ablation of MDR1 P-Glycoprotein

In vivo Study of the Inflammatory Modulating Effects of Low Level Laser Therapy on iNOS Expression Using Bioluminescence Imaging

In Vivo Visualization of Cardiac Allograft Rejection and Trafficking Passenger Leukocytes Using Bioluminescence Imaging

Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro

Influence of irrigant needle depth in removing bioluminescent bacteria inoculated into instrumented root canals using real-time imaging in vitro

Inhibition of Lymphogenous Metastasis Using Adeno-Associated Virus-Mediated Gene Transfer of a Soluble VEGFR-3 Decoy Receptor

Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo

Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection

Lipopolysaccharide recognition protein, MD-2, facilitates cellular uptake of E. coli-derived plasmid DNA in synovium

Long-term tracing of adenoviral expression in rat and rabbit using luciferase imaging

Low Levels of Her2/neu Expressed by Ewing's Family Tumor Cell Lines Can Redirect Cytokine-Induced Killer Cells

Luciferase real-time bioluminescence imaging for the study of viral pathogenesis

Melanoma-specific expression in first-generation adenoviral vectors in vitro and in vivo [mdash] use of the human tyrosinase promoter with human enhancers

Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation

Monitoring Age-Related Susceptibility of Young Mice to Oral Salmonella enterica Serovar Typhimurium Infection Using an In Vivo Murine Model

Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model

Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models

Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria

Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration

Nasal IL-12p70 DNA prevents and treats intestinal allergic diarrhea

Near-infrared fluorescent RGD peptides for optical imaging of integrin alphavbeta3 expression in living mice

Near-infrared-emissive polymersomes: Self-assembled soft matter for in vivo optical imaging

NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation

Non-invasive imaging of a transgenic mouse model using a prostate-specific two-step transcriptional amplification strategy

Noninvasive biophotonic imaging for monitoring of catheter-associated urinary tract infections and therapy in mice

Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus

Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer

Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model

Noninvasive monitoring of target gene expression by imaging reporter gene expression in living animals using improved bicistronic vectors

Novel Fusion Protein Approach for Efficient High-Throughput Screening of Small Molecule-Mediating Protein-Protein Interactions in Cells and Living Animals

Nuclear Factor-{kappa}B Affects Tumor Progression in a Mouse Model of Malignant Pleural Effusion

Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene

phiC31 integrase confers genomic integration and long-term transgene expression in rat retina

Photonic Monitoring in Real Time of Vascular Endothelial Growth Factor Receptor 2 Gene Expression under Relaxin-Induced Conditions in a Novel Murine Wound Model

Potential applications of conventional and molecular imaging to biodefense research

Real-time in vivo bioluminescent imaging for evaluating the efficacy of antibiotics in a rat Staphylococcus aureus endocarditis model

Real-Time in Vivo Imaging of Stem Cells Following Transgenesis by Transposition

Real-time in vivo imaging of stem cells following transgenesis by transposition

Reduction of astrogliosis by early treatment of pneumococcal meningitis measured by simultaneous imaging, in vivo, of the pathogen and host response

Reoxygenation of Hypoxic Mice with 100% Oxygen Induces Brain Nuclear Factor-kappa B

Resistance to Intestinal Entamoeba histolytica Infection Is Conferred by Innate Immunity and Gr-1+ Cells

S100P Promotes Pancreatic Cancer Growth, Survival, and Invasion

Sequence-Specific Knockdown of EWS-FLI1 by Targeted, Nonviral Delivery of Small Interfering RNA Inhibits Tumor Growth in a Murine Model of Metastatic Ewing's Sarcoma

Serum amyloid a-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition

Small Hairpin RNAs Efficiently Inhibit Hepatitis C IRES-Mediated Gene Expression in Human Tissue Culture Cells and a Mouse Model

Targeted Elimination of Prostate Cancer by Genetically Directed Human T Lymphocytes

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections

Tightly-regulated suicide gene expression kills PSA-expressing prostate tumor cells

Topotecan Combination Chemotherapy in Two New Rodent Models of Retinoblastoma

Transcriptional regulation of a metastasis suppressor gene by Tip60 and [beta]-catenin complexes

Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism

Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes

Unraveling the complexicity of oncogenesis through in vivo optical imaging

Valproic acid enhances gene expression from viral gene transfer vectors

Vascular Endothelial Cell Growth Factor Receptor 3-Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels

Vascular Endothelial Growth Factor-A Promotes Peritumoral Lymphangiogenesis and Lymphatic Metastasis

Visualization of a primary anti-tumor immune response by positron emission tomography

Whole-body bioluminescent imaging of human uveal melanoma in a new mouse model of local tumor growth and metastasis

2004

A Cyp1a2-luciferase transgenic CD-1 mouse model: responses to aryl hydrocarbons similar to the humanized AhR mice

A genetic reporter of thermal stress defines physiologic zones over a defined temperature range

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging

A potential role for imaging technology in anticancer efficacy evaluations

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy

Bioluminescence detection of cells having stabilized p53 in response to a genotoxic event

Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy

Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus

Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors

Bioluminescent imaging of Cdk2 inhibition in vivo

Bioluminescent monitoring of islet graft survival after transplantation

Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth

Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22

Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals

Combined in vivo bioluminescence and fluorescence imaging for cancer gene therapy

CXCR4 regulates growth of both primary and metastatic breast cancer

Development and application of CD19-specific T cells for adoptive immunotherapy of B cell malignancies

Differential regulation of the human CYP3A4 promoter in transgenic mice and rats

Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model

Establishment of Cre/LoxP recombination system in transgenic rats

Extracellular replication of Listeria monocytogenes in the murine gall bladder

Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease

High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of split Renilla luciferase

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice

Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer

Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine

Imaging tri-fusion multimodality reporter gene expression in living subjects

In vivo activity of nuclease-resistant siRNAs

In vivo bioluminescence imaging

In vivo bioluminescence imaging for integrated studies of infection

In vivo bioluminescence imaging of locally disseminated colon carcinoma in rats

In vivo bioluminescent imaging of virus-mediated gene transfer and transduced cell transplantation in the intervertebral disc

In vivo bioluminescent monitoring of chemical toxicity using heme oxygenase-luciferase transgenic mice

In vivo imaging of activated estrogen receptors in utero by estrogens and bisphenol A

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts

In vivo real-time imaging of TGF-beta-induced transcriptional activation of the RANK ligand gene promoter in intraosseous prostate cancer

In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system

Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals

Maturational differences in lung NF-kappaB activation and their role in tolerance to hyperoxia

Molecular imaging applications for immunology

Molecular imaging of drug-modulated protein-protein interactions in living subjects

Molecular imaging of homodimeric protein-protein interactions in living subjects

Molecular imaging of the biological effects of quercetin and quercetin-rich foods

Multi-modality imaging identifies key times for annexin V imaging as an early predictor of therapeutic outcome

Multimodality imaging of lymphocytic migration using lentiviral-based transduction of a tri-fusion reporter gene

Multimodality in vivo molecular-genetic imaging

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

Non-invasive imaging of GFAP expression after neuronal damage in mice

Noninvasive imaging of enhanced prostate-specific gene expression using a two-step transcriptional amplification-based lentivirus vector

Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene

Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein

Noninvasive optical imaging method to evaluate postantibiotic effects on biofilm infection in vivo

Novel bidirectional vector strategy for amplification of therapeutic and reporter gene expression

Optical imaging of Renilla luciferase, synthetic Renilla luciferase, and firefly luciferase reporter gene expression in living mice

Optimizing luciferase protein fragment complementation for bioluminescent imaging of protein-protein interactions in live cells and animals

Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium

Overriding imatinib resistance with a novel ABL kinase inhibitor

Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models

Real-time imaging and quantification of bioluminescent bacteria in root canals in vitro

Real-time imaging of peroxisome proliferator-activated receptor-gamma coactivator-1alpha promoter activity in skeletal muscles of living mice

Recent advances in imaging the lungs of intact small animals

Schedule-dependent Inhibition of Hypoxia-inducible Factor-1{alpha} Protein Accumulation, Angiogenesis, and Tumor Growth by Topotecan in U251-HRE Glioblastoma Xenografts

Shifting foci of hematopoiesis during reconstitution from single stem cells

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

Systemic tumor targeting and killing by Sindbis viral vectors

Targeted photodynamic therapy of established soft-tissue infections in mice

The characterization and hormonal regulation of kidney androgen-regulated protein (Kap)-luciferase transgenic mice

The EZC-prostate model: noninvasive prostate imaging in living mice

Tissue- and time-dependent estrogen receptor activation in estrogen reporter mice

Tissue-specific contributions of pneumococcal virulence factors to pathogenesis

Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse

Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor

Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice

Using sindbis viral vectors for specific detection and suppression of advanced ovarian cancer in animal models

Visualization of the dynamics of gene expression in the living mouse

2003

A potent and specific morpholino antisense inhibitor of hepatitis C translation in mice

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene

Advancing molecular therapies through in vivo bioluminescent imaging

An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice

Animal models of bone metastasis

Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells

Bioluminescence imaging reveals systemic dissemination of herpes simplex virus type 1 in the absence of interferon receptors

Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis

Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model

Breaching biological barriers: protein translocation domains as tools for molecular imaging and therapy

Comparison of gene expression after intraperitoneal delivery of AAV2 or AAV5 in utero

Current advances in molecular imaging: noninvasive in vivo bioluminescent and fluorescent optical imaging in cancer research

Direct continuous method for monitoring biofilm infection in a mouse model

Dynamic tracking of human hematopoietic stem cell engraftment using in vivo bioluminescence imaging

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus

Imaging 26S proteasome activity and inhibition in living mice

In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship

In vivo molecular-genetic imaging: multi-modality nuclear and optical combinations

In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer

Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification

Interrogating androgen receptor function in recurrent prostate cancer

Luciferase imaging of a neurotropic viral infection in intact animals

Membranous cells in nasal-associated lymphoid tissue: a portal of entry for the respiratory mucosal pathogen group A streptococcus

Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragment-assisted complementation

Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination

Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice

Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice

Optical imaging of transferrin targeted PEI/DNA complexes in living subjects

Optimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy

Organ-specific models of Streptococcus pneumoniae disease

Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer

Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection

Real-time monitoring of bacterial infection in vivo: development of bioluminescent staphylococcal foreign-body and deep-thigh-wound mouse infection models

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy

Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging

Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae

SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model

The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice

Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice

Treatment of autoimmune disease by adoptive cellular gene therapy

2002

Adoptive cellular gene therapy of autoimmune disease

Advances in in vivo bioluminescence imaging of gene expression

Advancing animal models of neoplasia through in vivo bioluminescence imaging

Determinants of hepatitis C translational initiation in vitro, in cultured cells and mice

Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents

It's not just about anatomy: in vivo bioluminescence imaging as an eyepiece into biology

Molecular imaging of gene expression and efficacy following adenoviral-mediated brain tumor gene therapy

Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation

Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice

Noninvasive imaging of cationic lipid-mediated delivery of optical and PET reporter genes in living mice

Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice

Noninvasive real-time imaging of apoptosis

Optical imaging of cardiac reporter gene expression in living rats

Optical imaging of Renilla luciferase reporter gene expression in living mice

Production of human clotting Factor IX without toxicity in mice after vascular delivery of a lentiviral vector

RNA interference in adult mice

Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1

The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model

Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation

Understanding immune cell trafficking patterns via in vivo bioluminescence imaging

Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging

Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3

Whole-animal cellular and molecular imaging to accelerate drug development

2001

Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit

Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis

In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression

In vivo imaging of light-emitting probes

Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice

Picture perfect

Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression

Revealing the spatiotemporal patterns of bacterial infectious diseases using bioluminescent pathogens and whole body imaging

Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters

Validation of a noninvasive, real-time imaging technology using bioluminescent Escherichia coli in the neutropenic mouse thigh model of infection

Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon

2000

Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct

Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging

Use of reporter genes for optical measurements of neoplastic disease in vivo

1999

Bioluminescence for biological sensing in living mammals

Humane science finds sharper and kinder tools

Noninvasive assessment of tumor cell proliferation in animal models

Visualizing the kinetics of tumor-cell clearance in living animals

1998

Bioluminescent indicators in living mammals

1997

Firefly gene lights up lab animals from inside out

Glowing mice illuminate gene expression patterns

Imaging brain structure and function, infection and gene expression in the body using light

Visualizing gene expression in living mammals using a bioluminescent reporter

1995

Photonic detection of bacterial pathogens in living hosts

1969

Development of bioactive peptide amphiphiles for therapeutic cell delivery