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2008

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Genome Res.
Volume: 18. Issue: 10. Pages: 1670-1679. Year: 2008. Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A.

Accelerated evolution of resistance in multidrug environments.
Proc Natl Acad Sci U S A.
Volume: 105. Issue: 37. Pages: 13977-13981. Year: 2008. Hegreness M, Shoresh N, Damian D, Hartl D, Kishony R.

Evidence for novel viruses by analysis of nucleic acids in virus-like particle fractions from Ambrosia psilostachya.
J Virol Methods.
Volume: 152. Issue: 1-2. Pages: 49-55. Year: 2008. Melcher U, Muthukumar V, Wiley GB, Min BE, Palmer MW, Verchot-Lubicz J, Ali A, Nelson RS, Roe BA, Thapa V, Pierce ML.

Use of simulated intestinal fluid for Caco-2 permeability assay of lipophilic drugs.
Int J Pharm.
Volume: 360. Issue: 1-2. Pages: 148-155. Year: 2008. Fossati L, Dechaume R, Hardillier E, Chevillon D, Prevost C, Bolze S, Maubon N.

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling
PNAS
Volume: 104. Issue: 50. Pages: 19936-19941. Year: 2007. Jeffrey Settlemen

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia
Blood
Volume: 111. Issue: 10. Pages: 5078-5085. Year: 2008. Mojca Jongen-Lavrencic1, Su Ming Sun1, Menno K. Dijkstra1, Peter J. M. Valk1, and Bob Löwenberg

Highly efficient peptide separations in proteomics Part 1. Unidimensional high performance liquid chromatography.
J Chromatogr B Analyt Technol Biomed Life Sci.
Volume: 866. Issue: 1. Pages: 48-63. Year: 2008. Sandra K, Moshir M, D'hondt F, Verleysen K, Kas K, Sandra P.

Vitamin K Epoxide Reductase Complex Subunit 1 (VKORC1) Polymorphism and Aortic Calcification
Arterioscler Thromb Vasc Biol.
Volume: 28. Issue: 4. Pages: 771-776. Year: 2008. Teichert M, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, De Smet PA, Witteman JC, Stricker BH.

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.
Am J Hum Genet.
Volume: 82. Issue: 2. Pages: 411-423. Year: 2008. Kayser M, Liu F, Janssens AC, Rivadeneira F, Lao O, van Duijn K, Vermeulen M, Arp P, Jhamai MM, van Ijcken WF, den Dunnen JT, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, de Jong PT, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, van D

2007

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Proc Natl Acad Sci U S A.
Volume: 104. Issue: 50. Pages: 19936-19941. Year: 2007. McDermott U, Sharma SV, Dowell L, Greninger P, Montagut C, Lamb J, Archibald H, Raudales R, Tam A, Lee D, Rothenberg SM, Supko JG, Sordella R, Ulkus LE, Iafrate AJ, Maheswaran S, Njauw CN, Tsao H, Drew L, Hanke JH, Ma XJ, Erlander MG, Gray NS, Haber DA, S

Automated, quantitative screening assay for antiangiogenic compounds using transgenic zebrafish.
Cancer Res.
Volume: 67. Issue: 23. Pages: 11386-11392. Year: 2007. Tran TC, Sneed B, Haider J, Blavo D, White A, Aiyejorun T, Baranowski TC, Rubinstein AL, Doan TN, Dingledine R, Sandberg EM.

Methods of using click chemistry in the discovery of enzyme inhibitors.
Nat Protoc.
Volume: 2. Issue: 11. Pages: 2655-2664. Year: 2007. Srinivasan R, Li J, Ng SL, Kalesh KA, Yao SQ.

Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study.
J Clin Oncol.
Volume: 25. Issue: 34. Pages: 5410-5417. Year: 2007. Modi S, Stopeck AT, Gordon MS, Mendelson D, Solit DB, Bagatell R, Ma W, Wheler J, Rosen N, Norton L, Cropp GF, Johnson RG, Hannah AL, Hudis CA.

R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies.
Br J Cancer.
Volume: 97. Issue: 10. Pages: 1344-1353. Year: 2007. Arts J, Angibaud P, Mariën A, Floren W, Janssens B, King P, van Dun J, Janssen L, Geerts T, Tuman RW, Johnson DL, Andries L, Jung M, Janicot M, van Emelen K.

Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.
Antimicrob Agents Chemother.
Volume: 51. Issue: 11. Pages: 3915-3923. Year: 2007. Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR

The catechol-O-methyltransferase Met158 low-activity allele and association with nonvertebral fracture risk in elderly men.
Clin Endocrinol Metab.
Volume: 92. Issue: 8. Pages: 3206-3212. Year: 2007. Stolk L, van Meurs JB, Jhamai M, Arp PP, van Leeuwen JP, Hofman A, de Jong FH, Pols HA, Uitterlinden AG

Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity.
Antimicrob Agents Chemother.
Volume: 51. Issue: 7. Pages: 2293-2303. Year: 2007. White LK, Yoon JJ, Lee JK, Sun A, Du Y, Fu H, Snyder JP, Plemper RK.

The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study.
Calcif Tissue Int.
Volume: 81. Issue: 1. Pages: 18-25. Year: 2007. Yazdanpanah N, Rivadeneira F, van Meurs JB, Zillikens MC, Arp P, Hofman A, van Duijn CM, Pols HA, Uitterlinden AG

Automation of Cell-Based and Noncell-Based Permeability Assays
Journal of the Association for Laboratory Automation
Volume: 12, Issue 2. Issue: . Pages: 104-109. Year: 0. L . Kellard , M . Engelstein

Maximizing the Identification of Leads from Compound Mixtures
Letters in Drug Design & Discovery
Volume: 4. Issue: 3. Pages: 215-223. Year: 2007. Warrior, Usha1; Gopalakrishnan, Sujatha M.1; Traphagen, Linda1; Freiberg, Gail1; Towne, Danli1; Humphrey, Patrick1; Kofron, James1; Burns, David J

High throughput drug screening for human immunodeficiency virus type 1 reactivating compounds.
Assay Drug Dev Technol.
Volume: 5. Issue: 2. Pages: 181-189. Year: 2007. Jones J, Rodgers J, Heil M, May J, White L, Maddry JA, Fletcher TM 3rd, Shaw GM, Hartman JL 4th, Kutsch O.

TGF-beta1 polymorphisms and arterial stiffness; the Rotterdam Study
Journal of Human Hypertension
Volume: 21. Issue: 6. Pages: 431-437. Year: 2007. Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Hoeks AP, Reneman RS, Asmar R, van Duijn CM, Witteman JC

Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage
Volume: 629. Issue: 1. Pages: 49-63. Year: 2007. Robert Gealya, Jennifer L. Wright-Bourquea, Andrew R. Kraynaka, Troy W. McKelveyb, John E. Barnuma and Richard D. Storera

The WiscDsLox T-DNA collection: an arabidopsis community resource generated by using an improved high-throughput T-DNA sequencing pipeline.
J Plant Res.
Volume: 120. Issue: 1. Pages: 157-165. Year: 2007. Woody ST, Austin-Phillips S, Amasino RM, Krysan PJ.

2006

Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis.
Proc Natl Acad Sci U S A.
Volume: 103. Issue: 28. Pages: 10606-10611. Year: 2006. Nören-Müller A, Reis-Corrêa I Jr, Prinz H, Rosenbaum C, Saxena K, Schwalbe HJ, Vestweber D, Cagna G, Schunk S, Schwarz O, Schiewe H, Waldmann H.

The BARD1 Cys557Ser variant and breast cancer risk in Iceland.
PLoS Med.
Volume: 3. Issue: 7. Pages: 217. Year: 2006. Stacey SN, Sulem P, Johannsson OT, Helgason A, Gudmundsson J, Kostic JP, Kristjansson K, Jonsdottir T, Sigurdsson H, Hrafnkelsson J, Johannsson J, Sveinsson T, Myrdal G, Grimsson HN, Bergthorsson JT, Amundadottir LT, Gulcher JR, Thorsteinsdottir U, Kong A

Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases.
Org Biomol Chem.
Volume: 4. Issue: 11. Pages: 2233-2240. Year: 2006. Seibert SF, Eguereva E, Krick A, Kehraus S, Voloshina E, Raabe G, Fleischhauer J, Leistner E, Wiese M, Prinz H, Alexandrov K, Janning P, Waldmann H, König GM.

Using small molecules to overcome drug resistance induced by a viral oncogene.
Cancer Cell.
Volume: 9. Issue: 2. Pages: 133-146. Year: 2006. Smukste I, Bhalala O, Persico M, Stockwell BR.

3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors.
Bioorg Med Chem Lett.
Volume: 16. Issue: 1. Pages: 59-63. Year: 2006. Weide T, Arve L, Prinz H, Waldmann H, Kessler H.

2005

Development of a high-throughput robotic fluorescence-based assay for HsEg5 inhibitor screening
Anal Biochem.
Volume: 345. Issue: 2. Pages: 326-335. Year: 2005. Bin Zhang , , David Senator, Christopher J. Wilson and Shi-Chung Ng

A High-Throughput System for the Rapid Extraction of Plant Genomic DNA for Genome Mapping and Marker-Assisted Breeding Studies
Journal of the Association for Laboratory Automation
Volume: 10. Issue: 4. Pages: 242-245. Year: 2005. Wang , K . Song , C . Kreader , S . Weber , J . Van Dinther , R . Valdes-Camin

Screens using RNAi and cDNA expression as surrogates for genetics in mammalian tissue culture cells.
Cold Spring Harb Symp Quant Biol.
Volume: 70. Issue: . Pages: 449-459. Year: 2005. Pearlberg J, Degot S, Endege W, Park J, Davies J, Gelfand E, Sawyer J, Conery A, Doench J, Li W, Gonzalez L, Boyce FM, Brizuela L, Labaer J, Grueneberg D, Harlow E.

2004

A Flexible Data Analysis Tool for Chemical Genetic Screens . Chemistry & Biology
Volume: 11, Issue 11. Issue: . Pages: 1495-1503. Year: 0. Kelley , M . Lunn , D . Root , S . Flaherty , A . Martino , B . Stockwell

Real-time imaging of peroxisome proliferator-activated receptor-gamma coactivator-1alpha promoter activity in skeletal muscles of living mice
Volume: 287. Issue: . Pages: C790-6. Year: 2004. T. Akimoto, B.S. Sorg, Z. Yan

2003

Glutathione S-transferase pull-down assays using dehydrated immobilized glutathione resin
Volume: 322. Issue: 2. Pages: 164-169. Year: 2003. Ling Rena, Edith Changa, Khadijah Makkyb, Arthur L. Haasb, Barbara Kaboorda and M. Walid Qoronfleh

A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor.
Neuron
Volume: 40. Issue: 4. Pages: 685-694. Year: 2003. Pollitt SK, Pallos J, Shao J, Desai UA, Ma AA, Thompson LM, Marsh JL, Diamond MI.

Localization of a gene for migraine without aura to chromosome 4q21.
Am J Hum Genet.
Volume: 73. Issue: 5. Pages: 986-993. Year: 2003. Björnsson A, Gudmundsson G, Gudfinnsson E, Hrafnsdóttir M, Benedikz J, Skúladóttir S, Kristjánsson K, Frigge ML, Kong A, Stefánsson K, Gulcher JR.

Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity
Biochem Biophys Res Commun.
Volume: 310. Issue: 1. Pages: 84-93. Year: 2003. James C. Burnetta, James J. Schmidtb, Robert G. Staffordb, Rekha G. Panchala, Tam L. Nguyena, Ann R. Hermonea, Jonathan L. Vennerstromc, Connor F. McGratha, Douglas J. Lanea, Edward A. Sausvillea, Daniel W. Zaharevitza, Rick Gussio , , a and Sina Bavari

Studies on Repository Compound Stability in DMSO under Various Conditions
Journal of Biomolecular Screening
Volume: 8. Issue: 3. Pages: 292-304. Year: 2003. Jill Hochlowski Hua Tang Darlene Hepp Carl Beckner Stan Kantor Robert Schmitt

SwellGel: a sample preparation affinity chromatography technology for high throughput proteomic applications.
Protein Expr Purif.
Volume: 28. Issue: 2. Pages: 270-279. Year: 2003. Haney PJ, Draveling C, Durski W, Romanowich K, Qoronfleh MW.

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
Cancer Cell
Volume: 3. Issue: 3. Pages: 285-296. Year: 2003. Dolma S, Lessnick SL, Hahn WC, Stockwell BR.

2001

Dispensing Precision for the SciClone™ Automated Liquid Handling Workstation for 96-Channel Pipetting
Journal of the Association for Laboratory Automation
Volume: 6, Issue 6. Issue: . Pages: 66-70. Year: 2001. R . Willebrords

A Fully Automated High-throughput Nucleic Acid Purification System Using Silica Coated Magnetic Bead Technology
Journal of the Association for Laboratory Automation
Volume: 6. Issue: 6. Pages: 35-38. Year: 2001. C . Schade