A fully automated high-throughput nucleic acid purification system using silica coated magnetic bead technology

J. Lab. Autom.

C. Schade

The design of a fully automated high-throughput system for the purification of sequencing templates is described. Hardware, software, and chemistries have been optimized to suit the needs of high-throughput laboratories involved in genome sequencing projects. Using this system, up to 5760 samples (60 x 96-well plates) can be purified in less than 16 hours during a single unattended run. The system can also be configured to perform sequencing reaction setup for all 60 plates following template purification, extending total run times to < 24 hours. Final sequencing reactions are prepared in 384- well microplates.

2001
Volume: 6. Issue: 6. Pages: 3.