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Lab Automation and Liquid Handling Application Notes


Drug Discovery

Compound Distribution form Matrix Screenmates Tubes using the Caliper Sciclone ALH 3000

Integration of an automated Workstation for Cell-Based Assays on Permeable Support Systems

Improvements in High Content Cell-Based Assays using the Caliper Sciclone ALH 3000 and various Corning Microplates

Miniaturization and Automation of a Luciferase Reporter Gene Assay


Genomics

High Throughput Plasmid DNA Preparation Using PVDF Filter Plates on an Automated Workstation

High Throughput PCR Cleanup Using 384 Well Glass Fiber Filter Plates and Postive Pressure on an Automated Workstation

Preparing Agilent 2100 LabChips for RNA analysis using the Caliper Sciclone ALH 3000

Sciclone ALH Carryover Testing Using the Ultrasonic Wash Station and a 384-Cannula Array

Automation of the Eppendorf Perfectprep BAC 96 DNA Kit on the Caliper Life Sciences Sciclone ALH 3000

High Throughput Plasmid DNA Preparation Using a Megnetic Bead Kit on an Automated Workstation

Scalable automation of the TempliPhi(tm) DNA Sequencing Template Amplification and DYEnamic(tm) ET Terminator Sequencing Kits on the Sciclone ALH 3000

Efficient, Automated RNA Isolation Using Ambion MagMAX-96 Total RNA Isolation Kit on the Sciclone ALH 3000

Automation of the Ambion MagMAX-96 Viral RNA Isolation Kit on the Sciclone ALH 3000

Automated Antisense RNA Synthesis Using the Ambion MessageAmp II-96 aRNA Amplification Kit


Proteomics
 
Protein Crystallization:  Sitting Drop Plate Screen Set-up using Corning's 96 Well Crystallography Plate and Caliper's Sciclone ALH 3000


Performance Validation

Evaluation of Second Generation Disposable Tip Accuracy and Precision for the Sciclone ALH 3000 using the Artel MVS Calibration Kit

Dry Dispensing with the Caliper Sciclone ALH 3000 using Disposable Tips

Liquid Level Detection with the Caliper Sciclone ALH 3000

Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option

Prolonged Mechanical Stress Precision Testing on a Sciclone ALH Low Volume Head

Dispensing 0.5 uL to "Dry" 384 Plates with the Sciclone ALH

Sciclone ALH Bulk Dispense Precision Testing

384 Well Pipetting Precision and Accuracy Testing Using the Sciclone Advanced Liquid Handler

96 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array

Sciclone ALH 3000 Liquid Handler:  Functional Characterization of the High Volume Head Part 1: Plate-to-Plate Precision Testing


 Method Writing Tips

ALH 3000 Software v3.5: Using Excel Instructions and a Plate Normalization Example

Timing incubations using VBA in Caliper Sciclone Software v3.5